Donnel 5 mg (Donepezil Hydrochloride Monohydrate)

Adult dose

Administer 5 mg of donepezil hydrochloride once daily at bedtime. If unusual dreams, nightmares, or sleep disturbances occur, consider administering the medication in the morning. For 4-6 weeks, administer a dose of 5 mg and assess clinical response during this period, then it may be increased to 10 mg. When increasing to 10 mg daily, monitor for gastrointestinal adverse reactions closely. Underweight elderly women should administer only 5 mg daily.

Child dose

There is no experience using this medication in children.

This medication contains donepezil hydrochloride as the active ingredient and is used for the treatment of Alzheimer’s-type dementia symptoms. First, this medication should not be used in certain patients. Those who are allergic to this medication or its components, women who are pregnant or may become pregnant, and patients with lactose intolerance or certain genetic metabolic disorders should not take this medication. Additionally, patients with heart disease, asthma, chronic obstructive pulmonary disease, or a history of peptic ulcers should use this medication cautiously. This medication can affect heart rhythm and increase gastric acid secretion, which may worsen gastrointestinal issues. When taking this medication, various adverse reactions may occur, so caution is required. For example, heart-related issues, gastrointestinal bleeding, liver function abnormalities, neurological issues, muscle pain or weakness, and difficulty breathing may occur. If these symptoms arise, consult healthcare professionals immediately. This medication is not approved for other types of dementia aside from Alzheimer’s disease, and its therapeutic efficacy should be regularly evaluated. Furthermore, this medication may affect the ability to drive or operate machinery due to drowsiness, dizziness, or muscle spasms, so caution is necessary. Since this medication is metabolized in the liver, patients with compromised liver function or liver diseases should be careful. Especially, women who are pregnant or breastfeeding should avoid using this medication unless absolutely necessary, and should consult healthcare professionals in such cases. This medication can interact with other drugs, so inform healthcare professionals of any other medications being taken. The risk of heart-related side effects may increase when taken with certain antibiotics, antidepressants, or antiarrhythmics. In case of overdose, severe nausea, vomiting, bradycardia, respiratory depression, and other symptoms may arise, and immediate emergency care is required. Antidotes such as atropine may be used for overdose. Finally, this medication should be kept out of reach of children, and transferring it to another container should be avoided to prevent quality degradation or accidents.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in oral or ocular mucosa, shortness of breath or difficulty in breathing, asthma attacks, respiratory difficulties accompanied with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary issues

Mild side effects

• Nausea
• vomiting
• diarrhea
• decreased appetite
• dizziness
• insomnia
• drowsiness
• headache
• fatigue
• muscle pain

Store this medication in a tightly sealed container that is air-tight, and it is recommended to keep it at room temperature between 1°C to 30°C. This storage helps to maintain the efficacy of the medication for a longer period.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle