Medication info
Hyupibelin Tablet (Propiverine Hydrochloride)

Hyupibelin Tablet (Propiverine Hydrochloride)

Prescription medicationTabletOral
Ingredient · strength
Propiverine Hydrochloride›20mg / 1 tablet
Manufacturer / importer
Huons Meditec Co., Ltd.
Appearance
Odorless, white, flat, and round film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201603582 · Approved 2016.06.20 · Insurance code 670401210

Summary

Main use
Relief of symptoms of overactive bladder (including urinary urgency) and urinary frequency and incontinence associated with bladder disorders
Who takes it
Adults
Adult dose
Adults: Administer 20 mg of propiverine hydrochloride orally once daily after a meal. Adjust the dose as appropriate according to symptoms; if the effect is insufficient and there are no safety concerns, 20 mg may be taken up to twice daily.

Ingredients

Manufacturer
Huons Meditec Co., Ltd.

Efficacy & effects

Relief of symptoms of overactive bladder (including urinary urgency) and urinary frequency and incontinence associated with bladder disorders

  • Frequent urination
  • incontinence
  • neurogenic bladder
  • neurogenic frequent urination
  • unstable bladder
  • bladder irritability
  • chronic cystitis
  • chronic prostatitis
  • urgency
  • urge incontinence
View approved original text

This medication is used to improve frequent urination and incontinence caused by neurogenic bladder, neurogenic frequent urination, unstable bladder, chronic cystitis, and chronic prostatitis. It is also effective in treating urgency, frequent urination, and urge incontinence due to overactive bladder. In other words, it helps to improve various urination problems caused by bladder dysfunction.

How to take

Adult dose

Adults: Administer 20 mg of propiverine hydrochloride orally once daily after a meal. Adjust the dose as appropriate according to symptoms; if the effect is insufficient and there are no safety concerns, 20 mg may be taken up to twice daily.

Precautions

This medication should not be used in certain patients. Patients who are allergic to this drug or its ingredients must not take it. It should not be administered to patients with gastrointestinal problems where food or digestive materials do not pass well, as it may exacerbate symptoms. Patients with weak gastrointestinal or bowel motility may also experience worsening symptoms due to the action of this drug. In patients with difficult urination, there is a risk of deteriorating symptoms due to reduced bladder function. Patients with glaucoma, especially those with angle-closure glaucoma, should not take this medication as it may increase intraocular pressure and worsen symptoms. Patients with myasthenia gravis may also experience worsening symptoms due to the action of this drug. Attention is required for patients with serious heart problems, as side effects may include cardiac rhythm disorders. Patients with severe inflammation or abnormalities in the colon and those with severely impaired liver function should also avoid use. Additionally, patients with genetic metabolic disorders such as lactose intolerance should not use this medication due to the lactose it contains. This medication should be used cautiously in some patients. Patients with difficulty urinating need to be careful, as symptoms may worsen. Those with poor liver or kidney function may have difficulty metabolizing and excreting the drug, leading to side effects, and should exercise caution. Patients with Parkinson's disease or cerebrovascular diseases may experience worsening symptoms or psychological issues. Patients with hyperthyroid conditions may also have worsening symptoms, such as increased heart rate, due to the action of this drug. Elderly patients, who often have decreased liver and kidney function, should start at a low dose and take it cautiously. Patients with problems in the autonomic nervous system, heart diseases, benign prostatic hypertrophy, glaucoma, and other conditions also need to be cautious. When taking this medication, serious side effects such as mental disturbances, severe constipation or abdominal distension, abnormal heart rhythms, thrombocytopenia, renal function impairment, skin rash, acute glaucoma symptoms, liver function abnormalities, and myalgia may occur. If unusual symptoms appear, the patient should stop taking the medication immediately and consult with a healthcare professional. Caution is advised while driving or operating machinery, as symptoms like drowsiness, dizziness, and vision impairment may occur, and it is essential to verify the presence of other conditions that may cause similar symptoms before taking the medication. When taking this medication with other drugs, there may be interactions that increase side effects, so consultation with a doctor or pharmacist is necessary. Women who are pregnant or may become pregnant should avoid taking this medication, as its safety is not confirmed, and breastfeeding women are also advised to discontinue breastfeeding while taking it. It is best not to administer this drug to children, as safety has not been established. In case of overdose, severe neurological symptoms, gastrointestinal issues, and cardiac abnormalities may occur, necessitating immediate medical treatment at a hospital. This medication should be kept out of the reach of children and should not be transferred to another container, as this may lead to a decline in quality or risk of accidents.

Side effects

  • Hallucinations
  • delusions
  • paralytic ileus
  • constipation
  • abdominal distension
  • palpitations
  • extrasystoles
  • bradycardia
  • QT prolongation
  • ventricular tachycardia
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  • atrioventricular block
  • thrombocytopenia
  • renal impairment
  • urinary retention
  • Stevens-Johnson syndrome
  • fever
  • erythema
  • itching
  • conjunctival injection
  • stomatitis
  • increased intraocular pressure
  • acute glaucoma attack
  • nausea
  • headache
  • vision impairment
  • liver dysfunction
  • jaundice
  • myalgia
  • weakness
  • rhabdomyolysis
  • thirst
  • abdominal pain
  • nausea
  • vomiting
  • dyspepsia
  • diarrhea
  • anorexia
  • stomatitis
  • glossitis
  • dysuria
  • residual urine
  • loss of urinary urgency
  • dizziness
  • headache
  • numbness
  • drowsiness
  • insomnia
  • tremor
  • altered consciousness
  • perceptual disturbances
  • transient amnesia
  • Parkinsonian symptoms
  • dyskinesia
  • hypotension
  • hypertension
  • chest pain
  • hypersensitivity
  • rash
  • urticaria
  • control disorders
  • dry eye syndrome
  • elevated AST
  • elevated ALT
  • elevated ALP
  • elevated BUN
  • elevated creatinine
  • leukopenia
  • fatigue
  • lethargy
  • edema
  • altered taste
  • lumbago
  • hoarseness
  • sputum
  • agitation
  • heat due to decreased sweating
  • weakness
  • pharyngodynia
  • upper respiratory infection
  • cough
  • skin pigmentation
  • oliguria
  • leukocytosis
  • tinnitus
  • pain
  • delusions
  • agitation
  • generalized seizures
  • walking disturbances
  • speech disorders
  • mydriasis
  • urinary retention
  • tachycardia
  • hypertension
  • generalized flushing
  • liver dysfunction

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius. This helps to ensure the drug's effectiveness is preserved safely.

Appearance and packaging

Appearance

Odorless, white, flat, and round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.