Levotree Tablet (Levostapiride)

Adult dose

Adults: Administer 25 mg of levosulpiride orally 3 times daily before meals.

This medication should not be used by women who are pregnant or may become pregnant, as well as by nursing women. It should not be administered to patients with gastrointestinal bleeding, mechanical obstruction, or perforation, as it may stimulate gastrointestinal motility and be harmful. Avoid use in patients with specific tumors such as pheochromocytoma, as it may induce hypertension. Patients with hypersensitivity or intolerability to this medication should avoid taking it. It is safe not to administer this medication to patients with liver disease or those in the manic phase of bipolar disorder. Patients with breast-related conditions should exercise caution as the increased prolactin secretion from this medication may exacerbate symptoms. Patients with lactose intolerance or certain genetic metabolic disorders should not take this medication due to the lactose component. Hypertensive patients, children, and the elderly should be especially cautious when using this medication, and children in particular should avoid overdose as they are more prone to extrapyramidal symptoms. This medication may induce amenorrhea, hyperprolactinemia, gynecomastia, and other symptoms due to endocrine disorders; if any abnormal symptoms occur, discontinue use immediately. Extrapyramidal symptoms such as tremors, tongue twisting, and anxiety may rarely occur; if these symptoms appear, discontinue administration. Prolonged use may result in tardive dyskinesia symptoms such as involuntary movements around the mouth, which may persist even after discontinuation of the medication. Gastrointestinal symptoms such as dry mouth, heartburn, nausea, vomiting, diarrhea, and constipation may occur. Cardiac-related adverse reactions such as hypertension or arrhythmias may occur, so caution is required. Severe side effects known as neuroleptic malignant syndrome have been reported, and if high fever, muscle rigidity, or altered consciousness occurs, the medication should be discontinued immediately and urgent treatment sought. Allergic reactions such as rash or swelling may rarely occur, and in such cases, the medication should also be discontinued. It is advisable to avoid driving or operating machinery that requires concentration during this medication use. As this drug may interact with other medications, caution is particularly needed when used with anticholinergic agents, analgesics, digitalis preparations, other benzamide medications, alcohol, and drugs that prolong the QT interval. Women who are pregnant or breastfeeding should not take this medication as safety for the fetus and neonate has not been established. The elderly should carefully adjust the dosage and dosing intervals as renal function may decline, leading to prolonged drug retention in the body. This medication can suppress vomiting symptoms; caution is needed if vomiting occurs for other reasons. Animal studies have reported that this drug may affect reproductive function, and there may be an increased risk of certain tumors with prolonged high-dose administration.

• Amenorrhea
• galactorrhea
• gynecomastia
• tremors
• tongue twisting
• anxiety
• involuntary movements around the mouth
• thirst
• heartburn
• nausea

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. Additionally, it is best to keep the medication at room temperature that is neither too hot nor too cold, ideally between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness for a longer time.

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle