Lipistat Tablets 20 mg (Atorvastatin Calcium Hydrate)

Adult dosage

Atorvastatin is administered once daily in a dosage range of 10-80 mg, at any time of day regardless of food. The recommended initial dose for hyperlipidemia patients is 10 mg once daily; if greater reductions in LDL-cholesterol are needed, it may be started at 20 mg or 40 mg once daily. Within 2-4 weeks after initiation and/or dose adjustment, lipid levels should be analyzed to guide further dose adjustments.

Children's dosage

The recommended initial dose for pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17) is 10 mg once daily, with a recommended maximum dose of 20 mg daily. Dose adjustments should be made at intervals of at least 4 weeks based on treatment goals.

This medication may cause adverse muscle reactions, so if severe muscle pain or weakness occurs, discontinue use immediately and consult a physician. Due to potential effects on liver function, do not take this medication if you have liver disease or elevated liver enzyme levels. Pregnant women, women who may become pregnant, and nursing mothers should not take this medication and should use appropriate contraception while on it. This medication should not be administered to children, especially those under 10 years of age. Individuals with alcoholism or a history of liver disease should use this medication with caution and undergo regular liver function tests. This medication may interact with certain drugs, so inform a physician or pharmacist if you are taking other medications. Be cautious when taking this medication with foods or drugs that inhibit the CYP3A4 enzyme, like grapefruit juice, as it may increase blood concentrations of this medication, raising the risk of side effects. If you experience severe muscle pain, weakness, fatigue, accompanied by fever or malaise, contact a physician immediately for testing. If symptoms of hepatitis such as nausea, vomiting, fatigue, or jaundice occur while taking this medication, discontinue use immediately and seek medical attention. Elderly patients or those with renal function impairment are at higher risk for myopathy, requiring additional caution during use. In the event of an overdose, there are no specific antidotes, so seek medical treatment immediately for symptomatic care and undergo liver and muscle-related testing. Store in a place out of reach of children, and keep in the original container tightly sealed.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizure, altered consciousness, visual disturbances, paralysis, urination changes.

Mild side effects

• Fatigue
• malaise
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. Additionally, it is recommended to store the medication at room temperature between 1 to 30 degrees Celsius, avoiding excessively hot or cold conditions.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle