Medication info
Lafurin Tablet 10 mg (Lansoprazole)

Lafurin Tablet 10 mg (Lansoprazole)

Prescription medicationTabletOral
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Farmgen Science Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201603257 · Approved 2016.06.07 · Insurance code 670104640

Summary

Main use
Treatment of gastrointestinal disorders (including ulcers and gastritis); pre-anesthetic medication; adjunctive treatment for Helicobacter pylori eradication
Who takes it
Adults
Adult dose
1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials of up to 8 weeks, most ulcers healed within 8 weeks, although the healing time may occasionally vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials of up to 6 weeks, most ulcers healed within 6 weeks, although the healing time may occasionally vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials of up to 2 weeks, most lesions healed within 2 weeks, although the healing time may occasionally vary among patients. 4. Antibiotic combination therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine per administration, given orally twice (before bedtime on the day before surgery and 2 hours before administration of anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

Ingredients

Manufacturer
Farmgen Science Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (including ulcers and gastritis); pre-anesthetic medication; adjunctive treatment for Helicobacter pylori eradication

  • Gastric ulcer
  • duodenal ulcer
  • acute gastritis
  • chronic gastritis gastric mucosal lesions
  • peptic ulcer
  • gastroesophageal reflux disease
View approved original text

This medicine is used to treat gastric ulcers and duodenal ulcers. It also helps improve gastric mucosal damage caused by acute and chronic gastritis, supporting gastric health. Administered together with antibiotics in patients with Helicobacter pylori infection, it enhances the therapeutic effect. The drug can be administered before anesthesia to regulate gastric acid secretion. Finally, it is effective in alleviating symptoms of gastroesophageal reflux disease. It is used to treat and improve various gastrointestinal-related disorders.

How to take

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials of up to 8 weeks, most ulcers healed within 8 weeks, although the healing time may occasionally vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials of up to 6 weeks, most ulcers healed within 6 weeks, although the healing time may occasionally vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials of up to 2 weeks, most lesions healed within 2 weeks, although the healing time may occasionally vary among patients. 4. Antibiotic combination therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine per administration, given orally twice (before bedtime on the day before surgery and 2 hours before administration of anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

Precautions

This drug should not be used in patients allergic to any components of this medicine. Since it contains lactose, patients with lactose intolerance or certain genetic metabolic disorders should avoid taking it. Patients with a history of drug hypersensitivity, liver or kidney function issues, those undergoing dialysis, and the elderly should use this drug with caution. Severe allergic reactions may occur while taking this medicine. If symptoms such as pallor, low blood pressure, or difficulty breathing appear, discontinue use immediately and notify healthcare personnel. Liver dysfunction or jaundice symptoms may occur, so liver function should be monitored regularly, and if abnormalities are found, the medication should be discontinued. A decrease in blood cell counts, agranulocytosis, or thrombocytopenia may arise; consult healthcare personnel immediately if symptoms like sore throat, fever, or general malaise occur. Rarely, serious side effects such as skin rashes, convulsions, and cardiac arrhythmias have been reported; discontinue use immediately if such symptoms appear. Gastrointestinal symptoms may include constipation, diarrhea, nausea, vomiting, abdominal bloating, and loss of appetite; central nervous system symptoms such as headache, insomnia, and drowsiness have also been reported. This drug may mask the symptoms of malignant tumors; thus, if symptoms of weight loss, repeated vomiting, or hematemesis occur, you must undergo examinations. Elderly patients have decreased body functions, so careful adjustment of dosage and intervals is necessary. Dialysis patients may have increased drug levels in their blood, so it should be started at a low dose and gradually increased. Pregnant women should take this drug only when the benefits outweigh the risks, according to a doctor's judgment, and breastfeeding women are advised not to take it as it may be excreted in breast milk. Safety in children has not been established, so it is advisable not to use it in pediatric patients. Keep this medicine out of reach of children, store it in its original container, and avoid transferring it to other containers.

Side effects

  • Shock
  • anaphylaxis symptoms
  • facial pallor
  • hypotension
  • generalized rash
  • dyspnea
  • liver dysfunction
  • jaundice
  • agranulocytosis
  • pharyngodynia
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  • general fatigue
  • fever
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • seizures
  • interstitial nephritis
  • Stevens-Johnson syndrome
  • Reiter's syndrome
  • rhabdomyolysis
  • atrioventricular block
  • reduced contractility
  • constipation
  • diarrhea
  • hard stools
  • nausea
  • vomiting
  • abdominal distension
  • anorexia
  • headache
  • insomnia
  • drowsiness
  • reversible confusional state
  • hallucinations
  • consciousness disturbance
  • dizziness
  • chills
  • warmth sensation
  • flushing
  • leukocytosis
  • eosinophilia
  • leukopenia
  • erythrocytopenia
  • decreased hematocrit
  • elevated ALT
  • elevated AST
  • elevated Al-P
  • elevated γ-GTP
  • elevated T-Bil
  • elevated LDH
  • elevated TTT
  • abnormal urinary protein
  • elevated BUN
  • elevated serum uric acid
  • elevated Cl
  • delayed maturation
  • elevated Na
  • decreased K
  • gynecomastia
  • edema
  • fatigue
  • glossitis
  • headache
  • urticaria
  • skin rash
  • abdominal pain
  • dyspepsia
  • enteritis
  • gastric ulcer
  • erosive gastritis
  • duodenitis
  • bowel distension
  • nasopharyngitis
  • upper respiratory infection
  • bronchopneumonia
  • tinea
  • carotid artery stenosis
  • cough
  • oropharyngeal pain
  • oropharyngeal discomfort
  • wet cough
  • fatigue
  • chest pain
  • limb pain
  • arthralgia
  • neck pain
  • pruritus
  • acne
  • contusion
  • insomnia
  • non-alcoholic steatohepatitis

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly closed container to protect it from air and moisture. Also, it is recommended to keep the medicine at room temperature, ideally between 1°C and 30°C, without exposing it to extreme heat or cold.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.