Medication info

Cronin Soft Capsule (Clonixin Lysinate)

OTC medicationSoft capsuleOralApproval withdrawn
Ingredient · strength
Clonixin Lysinate›125mg / 1 capsule
Manufacturer / importer
South Korea Prime Pharmaceutical Co., Ltd.
Appearance
A blue transparent oblong soft capsule containing a light yellow content.
Packaging
10 capsules/PTP packaging
Approval status
Approval withdrawn

MFDS item code 201603096 · Approved 2016.05.31

This product's status changed to Approval withdrawn on 2024.02.06. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Relief of mild to moderate pain (e.g., headache, toothache, and muscle pain)
Who takes it
Adults
Adult dose
Adults: Administer 125∼250 mg of clonixin lysinate orally 3 times daily.

Ingredients

Manufacturer
South Korea Prime Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of mild to moderate pain (e.g., headache, toothache, and muscle pain)

  • Muscle pain
  • neuralgia
  • pain after trauma
  • pain after surgery
  • headache
  • toothache
  • earache
View approved original text

This medicine is used to relieve various mild to moderate pains such as muscle pain, neuralgia, pain after trauma and surgery, headache, toothache, and earache.

How to take

Adult dose

Adults: Administer 125∼250 mg of clonixin lysinate orally 3 times daily.

Precautions

This medication should be discussed with a doctor or pharmacist before taking if one regularly consumes more than three drinks a day, as drinking heavily may increase the risk of gastrointestinal bleeding when taking this medication. This medication may increase risks to the cardiovascular system. Non-steroidal anti-inflammatory drugs, including this medication, may increase the risk of serious cardiovascular diseases such as thrombosis, myocardial infarction, and stroke, especially in individuals with cardiovascular disease or risk factors. Therefore, it is essential to closely monitor for any cardiovascular symptoms during use. This medication may cause side effects related to the gastrointestinal system. Serious issues such as bleeding, ulcers, or perforation in the stomach or intestines can occur, and these side effects may develop without symptoms. Elderly individuals face a higher risk and should take caution. It is essential to monitor for symptoms of gastrointestinal bleeding or ulcers during use, and treatment should be obtained immediately if problems are suspected. This medication should not be taken by individuals with peptic ulcers, those who have gastrointestinal issues due to medication, those allergic to this medicine or its ingredients, or those with allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs. Additionally, it should not be taken by individuals before or after coronary artery bypass surgery, pregnant women or those who may become pregnant, individuals with severe liver or kidney diseases, severe heart failure, or inflammatory bowel disease patients such as Crohn's disease or ulcerative colitis. During treatment with this medication, caution is advised against combining it with other non-steroidal anti-inflammatory drugs, ACE inhibitors, angiotensin II receptor antagonists, aspirin, diuretics, lithium, methotrexate, anticoagulants of the coumarin type, cyclosporine, tacrolimus, antiplatelet agents, selective serotonin reuptake inhibitors, and corticosteroids. Combining with these medications may impact side effects or efficacy, so it is crucial to consult with professionals. Individuals with a history of peptic ulcers or children, the elderly, those with hypertension, fluid retention, or heart failure, those taking diuretics or ACE inhibitors, and individuals with a history of bronchial asthma, liver or kidney disease should consult a doctor, dentist, or pharmacist before taking this medication. This medication may be secreted in breast milk; therefore, nursing women should consider discontinuing breastfeeding or stopping the medication when taking this drug. If symptoms such as nausea, vomiting, diarrhea, abdominal pain, gastrointestinal bleeding, severe skin rash, anemia, liver function abnormalities, drowsiness, headache, etc., occur during use, immediately discontinue the medication and consult with a doctor or pharmacist. This medication should be taken at the minimum effective dose and for the shortest duration possible. Those with chronic diseases should undergo regular blood tests along with liver and kidney function tests. Additionally, it should be understood that this medication does not treat the cause of inflammation or pain but instead alleviates symptoms. This medication may worsen hypertension and cause fluid retention and edema; thus, patients with these symptoms should be particularly cautious. Long-term use might lead to kidney damage or liver function abnormalities, so regular monitoring is necessary. This medication may cause severe allergic reactions and significant adverse reactions related to the skin; if symptoms such as skin rash or difficulty breathing occur, consumption should be stopped immediately. This medication should be kept out of reach of children and should not be transferred to another container.

Side effects

Gastrointestinal bleeding, serious cardiovascular thrombotic reactions, myocardial infarction, stroke, bleeding of the stomach or intestines, ulcers, perforation, nausea, vomiting, diarrhea, constipation, abdominal pain, peptic ulcer, shock, rash, itching, anemia, elevated AST, elevated ALT, drowsiness, headache, dizziness, sweating, chills, altered state of consciousness, jaundice, fulminant hepatitis, liver necrosis, liver failure, exfoliative dermatitis, mucocutaneous syndromes, toxic epidermal necrolysis, fluid retention, edema, renal failure, symptoms of anemia, anaphylactic-like reactions, severe bronchospasm

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be kept in a tightly sealed container to avoid exposure to air or moisture. It is crucial to maintain a storage temperature between 1 to 30 degrees Celsius. Proper storage will help preserve the medication's effectiveness.

Appearance and packaging

Appearance

A blue transparent oblong soft capsule containing a light yellow content.

Package unit

10 capsules/PTP packaging

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.