Disae Capsule 50mg (Diacerein)

Adult dose

Adults: Administer 50∼100mg of diacerein per day orally after meals in 1∼2 divided doses. The dose may be adjusted as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

This medication should not be used by patients with inflammatory bowel disease or those with bowel obstruction syndrome. Individuals with unexplained abdominal pain should also refrain from taking this medication. People allergic to this medication or its ingredients, or similar class drugs, should avoid using it. Patients with liver disease or a history of liver problems are advised not to take this medication. Children under 15 years of age should not use this medication. Additionally, this medication contains lactose, so those with lactose intolerance should avoid taking it. Patients with a history of small intestine or colon diseases should use this medication with caution. Women who are pregnant or breastfeeding should consult a doctor before taking this medication. Elderly individuals aged 65 and over should use a reduced dosage and be cautious. Those allergic to the ingredient Yellow No. 5 or have had hypersensitivity reactions should exercise caution when using this medication. This medication may cause gastrointestinal disturbances such as diarrhea, loose stools, and abdominal pain. Long-term use may lead to serious issues such as gastrointestinal bleeding, ulcers, or perforation; caution is required. Severe diarrhea can lead to dehydration or electrolyte imbalances, so if symptoms occur, consult a doctor immediately. Skin itching, rashes, or eczema may develop, and liver dysfunction may occur, albeit rarely. When taking this medication for an extended period, it is essential to follow the doctor's instructions. If diarrhea occurs, it is crucial to stop taking it and consult a physician. In case of severe diarrhea, caution is necessary as dehydration and electrolyte imbalance may result. If signs of liver damage appear, stop taking the medication immediately and inform a doctor, especially when used in conjunction with other medications that may stress the liver. Avoid alcohol consumption, as it may worsen liver damage. Taking antacids containing calcium, magnesium, or aluminum, or consuming salt can hinder the absorption of this medication, so it should be taken at least 2 hours apart. Caution is advised when used with diuretics, as diuretic effects may be intensified, leading to dehydration or hypokalemia. Taking this medication with cardiac glycosides, used to treat heart disease, may increase the risk of arrhythmias, so consulting a doctor is essential. Animal studies during pregnancy have reported delays in fetal bone formation, so it is safest for pregnant women not to use it. There is no clear data regarding humans, but since a small amount may be passed to infants through breast milk, it is also advisable for breastfeeding women not to take this medication. In case of overdose, severe diarrhea may occur, and treatment such as electrolyte supplementation may be necessary. If an overdose is suspected, seek appropriate medical treatment immediately.

Diarrhea, loose stools, abdominal pain, gastrointestinal disorders (bleeding, ulceration, and perforation), pigmentation of the rectal mucosa, dehydration, fluid and electrolyte imbalance, itching, rash, eczema, elevated liver enzymes in serum, hypokalemia, symptoms of liver damage, severe diarrhea

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is best kept at room temperature, between 1°C and 30°C, to maintain its effectiveness.

Appearance

A hard capsule with a yellow upper part and a light yellow lower part, containing a brownish-yellow substance.

Package unit

30 capsules/bottle, 500 capsules/bottle