Arovant 20 mg (Atorvastatin Calcium Trihydrate)

Adult dosage

The recommended initial dose for hyperlipidemia treatment is 10 mg of atorvastatin taken once daily, and if more LDL cholesterol reduction is needed, it can be started at 20 mg or 40 mg once daily. Generally, the drug is administered once daily within a range of 10 to 80 mg. Lipid levels should be analyzed and the dose adjusted every 2 to 4 weeks after starting treatment. For patients with homozygous familial hypercholesterolemia, the dose is 10 to 80 mg once daily.

Children's dosage

The recommended initial dose for pediatric patients (10 to 17 years) with heterozygous familial hypercholesterolemia is 10 mg once daily, with a maximum dose of 20 mg per day. Dosing adjustments should be made individually according to therapeutic goals.

This medication should be discontinued immediately if muscle-related abnormalities occur. Especially if muscle pain, muscle weakness, or muscle cramps occur along with a significant increase in creatine kinase levels, medical attention should be sought. This drug should not be used in patients with specific liver diseases or in those with severely impaired liver function. If liver function test results are significantly abnormal, the medication should be discontinued. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication, as it may be harmful to the fetus or nursing infant. This medication should not be administered to children, especially those under 10 years of age, as safety and efficacy have not been established. Care should be taken when using this medication in patients with certain conditions such as liver disease, renal impairment, hypothyroidism, or alcoholism, and regular monitoring should be conducted to assess their status. There may be interactions with other medications, so if the patient is currently taking any other medications, it is essential to inform the physician or pharmacist. Caution is especially needed when combining with certain antibiotics, antifungals, HIV treatments, and other lipid-lowering agents. During treatment with this medication, if symptoms such as liver function abnormalities, muscle pain, fatigue, or fever occur, the physician should be consulted immediately, and blood tests may be necessary to monitor liver and muscle status. This medication poses a higher risk of myopathy in alcohol abusers or the elderly, so these patients should be observed more closely. Appropriate contraceptive measures should be used during treatment, and if pregnancy is confirmed, the medication should be discontinued immediately and the healthcare provider should be consulted. When storing this medication, keep it out of reach of children, and it should be stored in the original container; it is safest not to transfer it to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination changes

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• rhinitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication should be stored in a tightly closed container to protect it from air and moisture. The storage temperature should maintain room temperature between 1 to 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle