Wish-150mg Capsule (Nizatidine)

Adult dose

1. Treatment of active gastric and duodenal ulcers Adults: Administer 300mg of nizatidine once daily at bedtime, or 150mg per dose orally twice daily, in the morning and evening. Most ulcers heal within 4 weeks, but treatment may be continued for up to 8 weeks if necessary. 2. Prevention of duodenal ulcer recurrence Adults: After healing of a duodenal ulcer, administer 150mg orally once daily at bedtime. Treatment may continue for up to 1 year; results of longer-term treatment are not known. 3. Gastroesophageal reflux disease Adults: Administer 150mg per dose orally twice daily, in the morning and evening. Treatment may continue for up to 12 weeks. 4. Improvement of gastric mucosal lesions Adults: Administer 150mg per dose orally twice daily, in the morning and evening, for 2 weeks. 5. Dosage adjustment for patients with severe renal impairment Dosage for patients with renal impairment should be reduced as follows. Creatinine clearance 20~50 ml/min: Active duodenal ulcer, gastroesophageal reflux disease (GERD), benign gastric ulcer: 150mg daily Creatinine clearance < 20 ml/min: Active duodenal ulcer, gastroesophageal reflux disease (GERD), benign gastric ulcer: 150mg every other day Maintenance therapy Creatinine clearance 20~50 ml/min: 150mg every other day Creatinine clearance < 20 ml/min: 150mg every 3 days

This medication should not be used in certain patients. Patients who have had hypersensitivity to this drug or other H2 receptor antagonists should not take this medication. Additionally, patients with lactose intolerance or certain genetic metabolic disorders should also avoid this drug. Caution is advised in patients with a history of drug hypersensitivity or impaired liver or kidney function. Particularly, patients with decreased kidney function may experience elevated drug concentrations, necessitating dosage adjustments or increased dosing intervals. This medication contains Yellow No. 5, so individuals allergic to this component should use it with caution. Rarely, allergic reactions such as skin rash, itching, and difficulty breathing may occur when taking this medication; if such symptoms arise, discontinue use immediately. Abnormal blood conditions, such as anemia or decreased white blood cell count, have been reported, so consult a physician if any abnormal symptoms occur. Gastrointestinal side effects may include constipation, diarrhea, dry mouth, and nausea. Liver function tests may rarely show elevated levels, or symptoms such as hepatitis and jaundice may occur, so attention to liver health is necessary. Symptoms such as confusion, headache, drowsiness, and dizziness may also occur, and seizures have been reported rarely. Increased heart rate may occur, and gynecomastia in women has been reported rarely. Skin-related adverse reactions such as sweating, hives, and skin rashes may occur. Rarely, symptoms unrelated to gout such as increased uric acid levels, fever, chest pain, muscle pain, rhinitis, pharyngitis, and cough have been reported. This medication may mask symptoms of gastric cancer, so it should only be used after confirming that the tumors are not malignant. It is primarily excreted through the kidneys; thus, in patients with impaired kidney function, dosage adjustments are necessary, and routine monitoring of blood, liver, and kidney function should be conducted during treatment. Women who are pregnant or breastfeeding should only use this medication when its benefits outweigh the risks, as its safety has not been adequately established. Especially for nursing mothers, it should only be administered when absolutely necessary, as the drug can be excreted in breast milk. Safety has not been established for children, and older adults may have reduced kidney function, so kidney function tests should be performed before administration; the condition of the kidneys should be closely monitored during treatment. No significant drug interactions have been reported with other specific medications; however, caution is required when used with high-dose aspirin. In cases of overdose, symptoms such as vomiting, diarrhea, and increased saliva may occur, and appropriate medical treatment should be sought immediately. This medication is not effectively removed by hemodialysis; thus, supportive care is necessary in cases of overdose.

• Rash
• itching
• bronchial asthma
• laryngeal swelling
• anaphylaxis symptoms
• anemia
• leukopenia
• neutrophilia
• thrombocytopenic purpura
• constipation

This medication may be sensitive to air or humidity, so it must be stored in a tightly closed container. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius. Proper storage will preserve the effectiveness of the medication.

Appearance

A hard capsule with yellow upper and pale yellow lower parts containing a whitish powder or granules.

Package unit

30 capsules/bottle, 300 capsules/bottle