Loxofil Tablet (Sodium Loxoprofen Hydrate)

Adult dose

1. For indications 1 and 2 ○ Adults: Administer Sodium Loxoprofen (anhydrous) 60 mg orally three times a day. For single therapy, take 60–120 mg orally. 2. For indication 3 ○ Adults: Administer Sodium Loxoprofen (anhydrous) 60 mg orally. In principle, it can be taken twice a day, with a maximum daily dose of 180 mg.

Individuals who regularly consume more than three alcoholic beverages a day should consult a doctor or pharmacist before taking this medication. Drinking alcohol while on this medication may increase the risk of gastrointestinal bleeding. This medication, along with other non-steroidal anti-inflammatory drugs, may increase the risk of cardiovascular diseases, so caution is needed for individuals with heart disease or risk factors. If cardiovascular symptoms occur, immediate medical attention is necessary, and patients should be informed about these symptoms and how to respond to them in advance. Additionally, this medication can lead to severe gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforation, hence those with a history of gastrointestinal disease and the elderly should be particularly cautious. If gastrointestinal bleeding symptoms or severe abdominal pain occur while taking this medication, cease use immediately and consult a physician. Those with certain conditions such as peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, or heart failure should not take this medication. Individuals with allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs, or those with a history of asthma should also refrain from using this medication. Pregnant women in late pregnancy, nursing mothers, and patients with inflammatory bowel disease should not take this medication. Patients with a history of peptic ulcers or diseases such as hypertension, kidney disease, liver disease, or asthma should use this medication cautiously under the guidance of a physician. This medication may cause various side effects including allergic reactions, skin rashes, gastrointestinal symptoms, liver dysfunction, and kidney impairment; if any unusual symptoms occur, discontinue use immediately and consult a doctor. Immediate emergency measures are required if severe skin rashes or allergic symptoms such as difficulty breathing or hives occur. This medication should be taken at the minimum effective dose for the shortest duration, and if used long-term, regular blood tests and liver and kidney function tests are necessary. Elderly patients or those with chronic conditions require more careful monitoring. It is advisable not to take this medication alongside other non-steroidal anti-inflammatory drugs, as it may interact with specific medications; hence it is crucial to inform the physician of any other medications being taken. Women who are pregnant or may become pregnant should consult a physician before use, and should strictly avoid it during late pregnancy. Nursing mothers should also refrain from taking this medication. Safety in children has not been established, so it is recommended not to use it in pediatric patients. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, peptic ulcer, perforation, hematemesis, melena, shock, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), erythema multiforme, acute generalized exanthematous pustulosis, jaundice, acute kidney failure, interstitial nephritis, difficulty breathing, asthma attacks, aseptic meningitis, severe allergic reactions, cardiovascular thrombotic reactions, myocardial infarction

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• stomach discomfort
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White circular tablet

Package unit

30 tablets/bottle, 100 tablets/bottle