Apito Tablet 20 Milligrams (Atorvastatin Calcium Trihydrate)

Adult dosage

For the treatment of hyperlipidemia, the recommended initial dose is 10 mg once daily; for patients requiring greater reduction of LDL-cholesterol, it may start at 20 mg or 40 mg once daily. Dosing is within a range of 10 to 80 mg once daily, individualized based on treatment goals and patient characteristics. Analyze lipid levels 2 to 4 weeks after starting treatment and adjust the dose accordingly. The treatment goal is to reduce LDL-cholesterol levels, so it's recommended to use LDL-cholesterol levels for evaluating treatment response. If LDL-cholesterol levels cannot be used, monitor treatment response using total cholesterol levels. For patients with homozygous familial hypercholesterolemia, the dosing is 10 to 80 mg once daily, administered in conjunction with other lipid-lowering therapies (e.g., LDL apheresis) or when these treatments are not feasible.

Children's dosage

The recommended initial dose for pediatric patients (10 to 17 years) with heterozygous familial hypercholesterolemia is 10 mg per day, with a maximum dose of 20 mg per day. The dosing should be adjusted according to treatment goals.

If symptoms of muscular issues occur, this medication should be discontinued immediately. Particularly, if muscle pain or weakness is severe or if blood tests show significantly elevated muscle damage markers, medical consultation is necessary. Patients with liver dysfunction or liver diseases should not take this medication and should undergo regular liver function tests during treatment. This medication should not be used by pregnant women, women who may become pregnant, or breastfeeding women. It should not be administered to children, especially those under 10 years of age. Patients with a history of alcoholism, liver disease, impaired kidney function, and elderly patients should use this medication with extra caution. This medication may have an increased risk of side effects when taken with certain drugs, so inform healthcare providers of any other medications being taken. In particular, dosage adjustments may be required when taken with medications that interfere with the metabolism of this drug in the liver. If sudden symptoms such as muscle pain, weakness, or fever occur during treatment, contact a physician immediately for evaluation. This medication should be stored out of reach of children and kept in its original container for safety. There is no specific antidote for overdose, so treatment should involve monitoring liver function and muscle damage and addressing symptoms as they arise.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, yellowing of the skin or eyes (jaundice), severe overall weakness, sudden and severe headache, thunderclap headache, seizures, confusion, vision disturbances, paralysis, significant reduction in urine output, severe swelling across the body with increased blood pressure, anaphylaxis

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• fever
• rhinitis
• hyperglycemia
• hypoglycemia
• weight gain
• loss of appetite

This medication should be stored in a tightly sealed container to protect it from air and moisture, preferably at room temperature between 1°C and 30°C. This will help maintain the efficacy of the medication for a longer period.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle