Imazole Tablet 40 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This drug should be swallowed with liquid such as water and must not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not treated or symptoms persist, continue for another 4 weeks. - Long-term maintenance therapy for recurrence prevention: 20 mg once daily. - Symptomatic treatment therapy: 20 mg once daily.

Children's dosage

Adolescents over 12 years 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not treated or symptoms persist, continue for another 4 weeks.

This medicine should not be administered to certain patients. For instance, patients with known allergies to this drug or its components, or those who have experienced hypersensitivity reactions to benzimidazoles, should not use it. Additionally, patients allergic to amoxicillin or clarithromycin, which are used in conjunction with this drug to eradicate Helicobacter pylori, should not take it. Women with a history of myocardial infarction or those who are breastfeeding should also refrain from using this medication. This drug may cause various adverse reactions, most commonly headaches, abdominal pain, diarrhea, and nausea, while less commonly blood abnormalities, allergic reactions, liver function abnormalities, and severe skin reactions have been reported. Particularly, long-term use may lead to hypomagnesemia, increased risk of fractures, and higher risk of gastrointestinal infections, thus regular monitoring is essential. This drug may interact with other medications, so caution is needed when taken with specific drugs. For example, co-administration with warfarin, methotrexate, or atazanavir may intensify side effects or alter efficacy. During pregnancy, the safety data of this drug is limited, so pregnant women should consult a doctor before use, and breastfeeding women are advised not to take this medication. In case of overdose, as there is no specific antidote, symptom-based treatment is crucial, and this drug is not removed through dialysis. Lastly, this drug should be stored out of reach of children, and care should be taken to maintain quality by not changing the storage container.

Serious side effects

Hives, severe swelling (edema), angioedema, anaphylaxis, shock, severe allergic reactions, skin peeling, pain in oral/ocular mucosa, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, erythema multiforme, drug reaction with eosinophilia and systemic symptoms, severe skin adverse reactions, difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, respiratory problems, yellowing of skin or eyes

Mild side effects

Headache, dizziness, sensory disturbances, drowsiness, taste disturbances, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, increased liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, joint pain, muscle pain, gynecomastia, weakness, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, facial edema, facial flushing, fatigue, fever, leg edema, malaise,

This medication must be stored in a tightly closed container to protect it from exposure to air and moisture. It is important to maintain room temperature between 1°C and 30°C. This will ensure the effectiveness and safety of the drug.

Appearance

Pink round film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu X 2)