Nuroxoronajeng (Loxoprofen Sodium Hydrate)

Adult dose

1. For efficacy and effects 1 and 2: Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally three times a day. For single-dose therapy, administer 60 to 120 mg orally. 2. For efficacy and effects 3: Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally. In principle, it can be administered twice a day, with a maximum of 180 mg per day. Avoid taking it on an empty stomach.

This medication should be taken with caution by individuals who consume more than three glasses of alcohol daily, as there is a risk of gastrointestinal bleeding; consultation with a doctor or pharmacist is necessary. Individuals with cardiovascular diseases or risk factors should be cautious, as this medication may cause cardiovascular events such as myocardial infarction or stroke during use. This medication can cause serious gastrointestinal side effects, such as gastrointestinal bleeding, ulcers, and perforation, so particular care should be taken for the elderly or those with a history of gastrointestinal diseases. Patients with peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, heart failure, or allergies to this medication's components should not take this medication. Individuals with a history of allergic reactions or asthma related to aspirin or other NSAIDs should also avoid this medication. This medication is contraindicated for pregnant women in the late stages of pregnancy, nursing mothers, and patients with inflammatory bowel diseases, such as Crohn's disease or ulcerative colitis. Caution is warranted for those with a history of peptic ulcers or those with liver or kidney function problems, and their condition should be closely monitored during treatment. This medication can produce various side effects, such as skin rash, respiratory distress, hypotension, serious gastrointestinal bleeding, liver dysfunction, and kidney dysfunction. If any unusual symptoms occur, stop taking the medication immediately and consult a healthcare professional. Long-term users should undergo regular blood tests and liver and kidney function tests to monitor for adverse effects. Combining with other non-steroidal anti-inflammatory drugs (NSAIDs) increases the risk of side effects, so it is advisable not to take them simultaneously. This medication may interact with various drugs, such as antihypertensives, diuretics, anticoagulants, lithium, and methotrexate. Therefore, if you are taking any other medications, you must inform your healthcare provider. Women who are pregnant or may become pregnant should carefully weigh the benefits and risks when using this medication and should not take it, especially in the late stages of pregnancy. It is safer not to take this medication while breastfeeding. Safety in pediatric patients is not established; hence, use in children is not recommended. Elderly patients are at increased risk of side effects, so extra caution is needed when taking this medication.

Serious side effects

Urticaria, severe swelling (edema), tightness in the chest, difficulty breathing, hypotension, respiratory distress, shock, anaphylactic-like symptoms, peptic ulcer, perforation, hematemesis, melena, shock, intestinal perforation, liver dysfunction (including jaundice), fulminant hepatitis, acute renal failure, acute respiratory distress, asthma attacks, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), erythema multiforme, acute systemic reactions.

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• discomfort in the stomach
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly closed container to prevent exposure to air or moisture and stored at a temperature between 1 and 30 degrees Celsius. This storage method helps maintain the medication's effectiveness and prevents degradation.

Appearance

White to light yellow round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle, 500 tablets/bottle