Welscaine Plus Cream

Adult dosage

1. Skin: After applying this drug, cover it with a sealing tape. The seal should usually be maintained for 1-3 hours on the application area, and the effect lasts for at least 1 hour after removing the sealing tape. (1) When inserting a needle (e.g., venipuncture, blood collection), apply approximately 2g for a minimum of 1 hour, up to a maximum of 5 hours. (2) For superficial surgical procedures (e.g., excision of warts), apply 1.5-2g/10 cm² for 1 hour. (3) For superficial surgical major procedures (e.g., ruptured skin grafts), apply 1.5-2g/10 cm² for a minimum of 2 hours, up to a maximum of 5 hours. 2. Genital mucosa: For condyloma removal, apply this drug approximately 5-10g for 5-10 minutes, then remove this drug and begin the procedure immediately. 3. Leg ulcers: After applying this drug, cover it with sealing tape. Use the opened tube for a single application and discard any remaining cream after each use. Apply 1-2g/10 cm² for at least 30 minutes, ensuring not to exceed 10g for each treatment. For leg ulcers of difficult penetration tissue, the application time can be extended to 60 minutes, and the ulcer should be washed within 10 minutes after removing the cream. If used up to 15 times over 1-2 months, there was no reduction in effectiveness or increase in local reactions.

Children's dosage

Infants 3 months to 12 months: Total amount 2g, does not exceed the application area of 16 cm².

This drug is used as a local anesthetic and can cause a blood condition known as methemoglobinemia. Patients with glucose-6-phosphate dehydrogenase deficiency, congenital methemoglobinemia, cardiac or pulmonary issues, infants under 6 months old, and those exposed to oxidizing agents may be more sensitive to this condition, and caution is necessary. Symptoms of methemoglobinemia, such as the skin turning blue or unusual blood color, should be closely monitored during use. If symptoms occur, discontinue use immediately and seek appropriate treatment. Additionally, this drug should not be used by patients with hypersensitivity to it, on areas with wounds or dermatitis, in infants under 3 months, and in infants under 12 months taking certain medications. Caution should be applied in patients with anemia, the frail, elderly patients, or those with severe liver disease, as the product contains substances that can provoke skin reactions. Temporary redness, swelling, pruritus, and in rare cases, severe allergic reactions or anaphylaxis may occur. It can cause irritation if it comes into contact with the eyes; therefore, it should not be applied near the eyes, and if contact occurs, the eyes should be immediately rinsed with clean water. The risk of side effects may increase when used with other specific medications, so patients should consult with their healthcare provider about any medications they are currently taking. During pregnancy, it should only be used if the benefits outweigh the risks, as determined by a physician, and caution is also necessary for nursing mothers. It should be used restrictively in children, especially infants under 3 months of age, and it is safer not to use it on the genital mucosa. In cases of overdose, methemoglobinemia and central nervous system and cardiovascular symptoms may appear, requiring immediate medical intervention, and patients showing symptoms should be closely monitored for several hours. The amount absorbed by the body can vary depending on the skin condition, application area, and duration of application, so caution is warranted during use. High doses and prolonged use should be avoided considering the potential for carcinogenicity.

Serious side effects

Anaphylactic shock. Methemoglobinemia. Seizures, coma, arrhythmias. Severe central nervous system disturbances. Severe allergic reactions in the eyes/skin. Severe liver abnormalities. Severe swelling or urination difficulties. Severe neurological symptoms (e.g., convulsions).

Mild side effects

Temporary local reactions such as pallor, redness, and swelling. Mild local sensitization reactions such as initial burning or pruritus. Numbness, skin irritation. Corneal irritation.

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain storage temperatures between 1°C and 30°C. This will help safely preserve the medication's effectiveness.

Appearance

White cream formulation

Package unit

500 grams/bottle, 450 grams/bottle