J-Brex Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment at 400 mg daily, consider another treatment option. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. Starting on the second day, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

Patients who consume large amounts of alcohol daily must consult with a doctor or pharmacist before taking this medication, as taking it with alcohol may cause gastrointestinal bleeding. This medication may increase the risk of cardiovascular or cerebrovascular diseases, so particular caution is needed for those with a history of cardiovascular diseases or risk factors. It should be used at the minimum effective dose and for the shortest duration possible, and cardiovascular symptoms should be reported to medical staff immediately. This medication can cause serious gastrointestinal issues, including ulcers, bleeding, and perforation. Elderly patients or those with a history of gastrointestinal diseases should be especially careful and must visit a hospital immediately if they experience symptoms such as epigastric pain, indigestion, black stools, or vomiting blood. This medication should not be used in patients with specific allergies, severely impaired liver or kidney function, active peptic ulcers, heart failure, or in pregnant or breastfeeding women. Patients with liver or kidney issues or histories of asthma, hypertension, or heart failure should use this medication with caution and require regular examinations. This medication can cause various side effects, including indigestion, headache, dizziness, hypertension, skin rashes, and liver dysfunction. If any of these symptoms occur, medical staff should be informed immediately. There may be interactions with other medications while taking this medication, so all medications being taken should be disclosed to the doctor or pharmacist. Women who are pregnant or planning to become pregnant should avoid taking this medication, and those who are breastfeeding should also avoid taking it. Elderly patients may be more susceptible to renal, hepatic, and cardiac function deterioration while taking this medication and should be monitored closely. Regular blood tests and assessments of liver and kidney function are required for patients taking this medication long-term, and the medication may need to be discontinued if there are abnormal findings. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and abdominal pain may occur, and immediate medical attention is necessary. Keep this medication out of reach of children and avoid storing it in containers other than the original packaging.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcer, hemorrhage, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tone increase, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, abdominal distension, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, pruritus, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, trauma, headache, leg cramps, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal hemorrhage, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized pustular eruption, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, menstrual disorders, female infertility, chest pain, vesicular dermatitis, dermatitis, nail disease, photosensitivity reaction, pruritus, erythematous rash, maculopapular rash, skin disease, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, skin-mucosal syndrome, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fracture, tendon rupture, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, phlebitis, contact dermatitis, injection site reaction, skin nodules, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, dizziness, constipation, thirst, ulcerative stomatitis, gastritis, allergy, lumbar pain, hyperlipidemia, hearing loss

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, and the storage temperature should be maintained between 15 to 30 degrees Celsius. This will help preserve the medication's effectiveness and prevent deterioration.

Appearance

A white to slightly yellow powder filled in a white hard capsule with blue stripes on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle