Sebocapsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be taken with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. 2. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks at 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment onward, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be used with caution if the patient regularly consumes a significant amount of alcohol, as it may cause gastrointestinal bleeding. It can also increase the risk of blood clots in the cardiovascular system, potentially leading to serious issues such as myocardial infarction or stroke. If cardiovascular symptoms occur, even in patients without a history of cardiovascular disease, immediate medical consultation is needed, and it should only be used at the lowest effective dose for the shortest duration. This medication may cause severe gastrointestinal issues such as ulcers, bleeding, or perforation, so caution is particularly necessary in elderly patients or those with a history of gastrointestinal diseases. If symptoms such as epigastric pain, indigestion, black stools, or vomiting occur, medical attention should be sought immediately. It should not be administered to individuals with specific allergic reactions, severe liver or kidney disease, heart failure, active peptic ulcer, inflammatory bowel disease, or pregnant or breastfeeding women. Patients with reduced liver or kidney function, asthma, hypertension, and those at high risk for cardiovascular disease need careful monitoring when using this medication. Various side effects may occur; common ones include indigestion, diarrhea, headache, dizziness, hypertension, cough, and skin rash. Severe skin reactions or allergic symptoms may appear, so if skin rash, blisters, fever, or itching symptoms occur, administration should be stopped immediately, and medical attention sought. This medication may affect liver and kidney function, necessitating regular blood tests and function tests, and it must be stopped if abnormalities are detected. It can interact with other medications, so inform your doctor or pharmacist of any other medications being taken, especially when using antihypertensives, diuretics, anticoagulants, and antidepressants. Pregnant women or those who may become pregnant should not take this medication, and breastfeeding women should avoid it or stop breastfeeding. The safety and effectiveness of this medication have not been established for children and adolescents under 18 years, so its use is not recommended. Elderly patients should be monitored closely due to potentially reduced liver, kidney, and heart function. Dizziness or drowsiness may occur, so driving or operating machinery should be avoided. In case of overdose, symptoms such as nausea, vomiting, lethargy, and gastrointestinal bleeding may occur, requiring immediate medical attention. This medication should be stored out of the reach of children, and transferring it to other containers is not advised to maintain quality.

Gastrointestinal bleeding, cardiovascular thrombotic response, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, abdominal distension, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, damage, taste disturbance, albuminuria, cystitis, hematuria, dysuria, urinary frequency, nephrolithiasis, urinary incontinence, urinary tract infection, visual confusion, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased blood creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, migraine, neuralgia, neuropathy, sensory disturbance, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized vesicular fixed drug eruption, fixed drug eruption, menstrual disorders, female infertility, chest pain, anaphylactic reaction, hallucinations, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitivity reaction, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, mesangial nephritis

This medication should be stored in a tightly sealed container to prevent air and moisture ingress, ideally at room temperature between 15 and 30 degrees Celsius. This ensures the safe maintenance of the medication's efficacy.

Appearance

A capsule with a white to light yellow powder filling.

Package unit

30 capsules, 100 capsules