Beasept 10 mg (Donepezil Hydrochloride Hydrate)

Adult dose

Adult: Administer 5 mg of Donepezil Hydrochloride once daily before bedtime. If sleep disturbances such as unusual dreams, nightmares, or insomnia occur, consider morning administration. The 5 mg dosage should be administered for 4 to 6 weeks, after which it can be increased to 10 mg based on clinical response. When increasing to 10 mg, caution should be taken regarding gastrointestinal adverse reactions. For underweight women aged 85 and over, the daily dosage should not exceed 5 mg.

Child dose

Pediatric: There is no experience using this medication in children.

This medicine contains Donepezil Hydrochloride Hydrate as its main ingredient and is primarily used for improving cognitive function in patients with Alzheimer's dementia. This medication should not be administered to certain patients. For example, individuals who are allergic to this drug or its components, women who are pregnant or may become pregnant, and nursing mothers should avoid taking it. Patients with heart diseases, especially those with sick sinus syndrome, cardiac conduction disturbances, bradycardia, or other heart rhythm issues should use this medication with caution, as it can stimulate the vagus nerve and cause bradycardia or arrhythmias. Those taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should be cautious of gastrointestinal bleeding or worsening of ulcers, as this medication can increase gastric acid secretion and gastrointestinal motility, potentially worsening symptoms. Patients with a history of asthma or obstructive lung disease should also exercise caution when taking this medication, as it may exacerbate symptoms due to bronchoconstriction or increased mucus secretion. Patients with extrapyramidal disorders such as Parkinson's disease may see a worsening of symptoms or the emergence of new symptoms as a result of this medication stimulating cholinergic nerves. Various adverse reactions may occur while taking this medication. Cardiac-related adverse reactions include syncope, bradycardia, heart block, and myocardial infarction, while gastrointestinal adverse reactions may include peptic ulcers, gastrointestinal bleeding, nausea, vomiting, and diarrhea. Additionally, serious adverse reactions such as liver dysfunction, seizures, movement disorders, dyskinesia, respiratory distress, acute pancreatitis, acute kidney failure, and sudden death may occur, and if any symptoms arise, immediate consultation with a physician is necessary. This medication may affect driving or operating machinery, so caution is advised at the beginning of treatment or upon dosage changes, as fatigue, dizziness, and muscle cramps may occur. This medication may interact with various other drugs, especially those metabolized in the liver. Therefore, it is essential to consult with a healthcare provider or pharmacist when taking other medications. Women who are pregnant or nursing should avoid taking this medication, and if it is absolutely necessary, discontinuing breastfeeding is recommended. In the case of overdose, serious symptoms such as nausea, vomiting, bradycardia, hypotension, respiratory depression, and convulsions may occur, necessitating immediate medical attention for proper treatment. This medication should be stored out of reach of children and should not be transferred to another container to maintain quality and safety.

Serious side effects

Syncope, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcers, perforated duodenal ulcers, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, seizures, cerebral hemorrhage, cerebrovascular disorders, movement disorders, ataxia, dyskinesia, dystonia, tremors, involuntary movements, gait disturbance, abnormal posture, speech difficulties, malignant neuroleptic syndrome (catatonia, severe muscle rigidity, dysphagia, tachycardia, hypertension)

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• dizziness
• insomnia
• hallucinations
• agitation

This medication should be stored in a sealed container to prevent air ingress, and it is recommended to keep it at a temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 60 tablets/bottle