Espalmon Tablets (Limaprost Alfa-Dex)

Adult dosage

1. For improvement of ischemic symptoms such as ulcers, pain, and coldness associated with thromboangiitis obliterans (Buerger disease), the usual adult dose is 2 tablets orally, 3 times daily. 2. For improvement of subjective symptoms (lower limb pain and numbness) and walking ability associated with acquired lumbar spinal canal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally, 3 times daily. The dose may be adjusted as appropriate according to age and symptoms.

This medication should not be used in women who are pregnant or may become pregnant. As it contains lactose, patients with lactose intolerance or specific genetic metabolic disorders should not take this medication. Patients with a tendency to bleed or those taking antiplatelet agents, thrombolytics, or anticoagulants should use this medication cautiously. While taking this medication, hypersensitivity reactions such as skin rash or itching may occur, and if these symptoms arise, the medication should be discontinued. Bleeding may rarely occur, so if bleeding symptoms present, stop taking the medication immediately and consult a physician. Gastrointestinal symptoms such as diarrhea, nausea, abdominal pain, decreased appetite, and heartburn may occur. Hepatic dysfunction may occur rarely, so regular liver function tests are recommended. Symptoms such as rapid heart rate, bluish discoloration of the hands and feet, and low blood pressure may rarely occur. Headaches, facial flushing, dizziness, warmth, feelings of heaviness or swelling, trembling, increased body hair on legs, or symptoms of anemia may occur. Patients with lumbar spinal canal stenosis should carefully monitor changes in symptoms and decide whether to continue the medication. The efficacy of this medication is uncertain for patients with severe lumbar spinal canal stenosis. Safety during pregnancy has not been established, and uterine contractions were observed in animal studies, so pregnant women should not take it. Safety in children has not been confirmed, so it is advisable not to administer it to children. Elderly patients may have decreased bodily functions, so dosage adjustments and careful monitoring are necessary. Healthy adults taking large amounts of this medication may experience a temporary drop in blood pressure, so prescribed dosages must be adhered to.

• Rash
• itching
• bleeding
• diarrhea
• nausea
• abdominal discomfort
• abdominal pain
• loss of appetite
• heartburn
• vomiting

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. Additionally, it is best to store the medication at room temperature between 1 degree and 30 degrees.

Appearance

White round tablet

Package unit

84 Tablets/Alu-Alu (21 Tablets/Alu-Alu X4)