Medication info
Esomeprazole Magnesium Trihydrate Tablet 20 mg

Esomeprazole Magnesium Trihydrate Tablet 20 mg

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Trihydrate›22.25mg / 1 tablet
Manufacturer / importer
아이큐어(주)
Appearance
Pale pink elongated film-coated tablet
Packaging
28 tablets/box [(7 tablets/Alu-Alu X 4)]
Approval status
Active

MFDS item code 201602142 · Approved 2016.04.18 · Insurance code 674400800

Summary

Main use
Treatment of gastroesophageal reflux disease (erosive reflux esophagitis, symptoms), treatment and prevention of relapse of Helicobacter pylori positive peptic ulcer, alleviation of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drugs, treatment and prevention of gastric and duodenal ulcers, treatment of Zollinger-Ellison syndrome, prevention of rebleeding in gastric and duodenal ulcers, and maintenance therapy.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with fluids, and it should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Long-term maintenance therapy to prevent recurrence in patients with esophagitis: 20 mg once daily - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: 20 mg once daily - As needed.
Children's dosage
Adolescents aged 12 and older - Treatment of gastroesophageal reflux disease - Erosive reflux esophagitis: 40 mg once daily for 4 weeks - Treatment of gastroesophageal reflux disease symptoms without esophagitis: once daily, 1 dose of

Ingredients

Manufacturer
아이큐어(주)

Efficacy & effects

Treatment of gastroesophageal reflux disease (erosive reflux esophagitis, symptoms), treatment and prevention of relapse of Helicobacter pylori positive peptic ulcer, alleviation of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drugs, treatment and prevention of gastric and duodenal ulcers, treatment of Zollinger-Ellison syndrome, prevention of rebleeding in gastric and duodenal ulcers, and maintenance therapy.

  • Gastroesophageal reflux disease
  • erosive reflux esophagitis
  • esophagitis
  • duodenal ulcer
  • peptic ulcer
  • upper gastrointestinal pain
  • upper gastrointestinal discomfort
  • upper gastrointestinal burning sensation
  • gastric ulcer
  • duodenal ulcer
  • Zollinger-Ellison syndrome
  • rebleeding.
View approved original text

This medication is used for the treatment of gastroesophageal reflux disease and erosive reflux esophagitis, and it is effective for long-term maintenance therapy to prevent recurrence in patients with esophagitis. Additionally, it helps treat symptoms of gastroesophageal reflux disease without esophagitis. It is used in combination with antibiotics to eradicate Helicobacter pylori and treat duodenal ulcers and peptic ulcers as well as preventing relapse. It is effective for managing upper gastrointestinal symptoms and gastric ulcers caused by taking non-steroidal anti-inflammatory drugs, and it is also used for treating Zollinger-Ellison syndrome. Additionally, it is used for maintenance therapy to prevent rebleeding in patients with bleeding gastric and duodenal ulcers. Overall, it is widely used for the treatment and prevention of gastrointestinal diseases.

Dosage and Administration

Adult dosage

This medication should be swallowed with fluids, and it should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Long-term maintenance therapy to prevent recurrence in patients with esophagitis: 20 mg once daily - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: 20 mg once daily - As needed.

Children's dosage

Adolescents aged 12 and older - Treatment of gastroesophageal reflux disease - Erosive reflux esophagitis: 40 mg once daily for 4 weeks - Treatment of gastroesophageal reflux disease symptoms without esophagitis: once daily, 1 dose of

Precautions

This medication should not be administered to patients with specific allergic reactions or history of hypersensitivity. Special caution is required for individuals who are sensitive to this drug or to benzimidazoles, penicillin antibiotics, and macrolide antibiotics. Furthermore, it is safer for women who have a history of certain heart conditions, those who are breastfeeding, and patients taking certain antiviral or heart-related medications not to use this medication. This medication contains the pigment Yellow No. 5, and those allergic to this component should use it with caution. Various adverse reactions may occur during use, so it is important to closely monitor changes in the body such as headaches, dizziness, gastrointestinal disorders, skin rashes, muscle pain, and blood abnormalities. Careful monitoring is necessary for long-term use, as electrolyte imbalances such as hypomagnesemia may occur. This medication inhibits gastric acid secretion, which may increase the risk of bacterial infections in the gastrointestinal tract; therefore, if diarrhea persists, consultation with a physician is necessary. Additionally, the risk of fractures may increase with long-term use, so caution is required in patients at risk of osteoporosis. Drug interactions may occur while taking this medication, so it is important to consult a doctor when taking it together with other medications, especially anticoagulants, antibiotics, antivirals, and anticonvulsants. In cases of pregnancy or breastfeeding, safety has not been sufficiently confirmed, so it is essential to consult a healthcare professional before use. In the event of overdose, there is no specific antidote, so it is important to visit a hospital immediately for appropriate treatment, and during storage, ensure it is kept out of reach of children and not transferred to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, anaphylaxis, shock, angioedema, severe hypomagnesemia, jaundice, hepatitis, liver failure, encephalopathy, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, eosinophilia and systemic symptoms drug reaction (DRESS syndrome), interstitial nephritis, Clostridium difficile-associated diarrhea, severe allergic reactions, severe skin reactions.

Mild side effects

Headache, dizziness, insomnia, anxiety, mental confusion, depression, aggression, hallucination, taste disturbance, blurred vision, bronchospasm, pancreatitis, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, gynecomastia, asthenia, increased sweating, Clostridium difficile-associated diarrhea, abdominal distension, allergies.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is important to maintain storage temperatures between 1 degree and 30 degrees Celsius. Doing so will help maintain the efficacy and safety of the medication over time.

Appearance and packaging

Appearance

Pale pink elongated film-coated tablet

Package unit

28 tablets/box [(7 tablets/Alu-Alu X 4)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.