Picox Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be administered with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment at 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day onward, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist before use in individuals who regularly consume more than three alcoholic drinks daily, as it may increase the risk of gastrointestinal bleeding when taken with this medication or other analgesics. This medication may increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke. These risks may increase with higher doses and longer duration, so it should be used at the lowest effective dose for the shortest duration possible. Serious adverse reactions such as gastrointestinal perforation, ulcers, or bleeding may occur. Particularly, elderly patients or those with a history of gastrointestinal disease should be cautious, and if symptoms such as epigastric pain, dyspepsia, black stool, or hematemesis occur, immediate medical attention is required. This medication should not be administered to certain patients, such as those allergic to this medication or its components, individuals allergic to sulfonamides, those with a history of allergy to aspirin or other non-steroidal anti-inflammatory drugs, severe liver or kidney impairment patients, patients with active peptic ulcer, pregnant or breastfeeding women. Patients with impaired liver or kidney function, hypertension, heart failure, asthma, and the elderly should use this medication with caution and require regular monitoring under a physician's guidance. Various adverse reactions may occur during treatment, including dyspepsia, headache, dizziness, hypertension, edema, skin rash, etc. If severe skin reactions or allergic symptoms occur, it is essential to discontinue use immediately and consult healthcare professionals. This medication may interact with various drugs, so inform a doctor or pharmacist if you are currently taking other medications, especially blood pressure medications, diuretics, anticoagulants, antidepressants, antibiotics, etc. Pregnant women or those planning to become pregnant should not take this medication, and if pregnancy occurs while on the medication, it should be discontinued immediately and a doctor consulted. Safety and efficacy in children and adolescents have not been established, so it is advisable not to use in individuals under 18 years of age. Elderly patients may have decreased liver and kidney function, so special care and monitoring are needed when using this medication. Regular blood tests and liver and kidney function tests are recommended during prolonged use, and if any abnormal findings are detected, dosing adjustments should be made after consulting with a doctor. In case of overdose, symptoms such as nausea, vomiting, drowsiness, and lethargy may occur, and immediate medical attention is necessary. This medication should be stored out of reach of children and should not be transferred to other containers for safety.

Gastrointestinal bleeding, cardiovascular thromboembolic reactions, myocardial infarction, stroke, upper and lower gastrointestinal tract perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, indigestion, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, dysgeusia, albuminuria, cystitis, hematuria, dysuria, nocturia, nephrolithiasis, urinary incontinence, urinary tract infections, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, anorexia, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal anomalies, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in the back, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, phlebitis, contact dermatitis, injection site reactions, skin nodules, chest pain, headache, dizziness, constipation, thirst, ulcerative stomatitis, gastritis, allergies, low back pain, hyperlipidemia, hearing loss, anaphylaxis, hallucinations, intracerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized pustular arthrodermatitis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility

This medication should be stored in a tightly sealed container to prevent air exposure, and the temperature should be maintained between 15 to 30 degrees Celsius. This storage method helps preserve the medication's efficacy and prevents degradation.

Appearance

Capsules filled with white to yellowish powder.

Package unit

30 capsules/bottle, 100 capsules/bottle