Nexera Tablet 40mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This drug should be swallowed with liquid, such as water, and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If necessary, an additional 4 weeks of treatment. - Maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily. - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: 20 mg once daily. After symptom relief,

Children's dosage

Adolescents over 12 years old 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If necessary, an additional 4 weeks of medication.

This drug should not be used in certain patients. For example, patients who are allergic to this drug or any of its components, have a hypersensitivity to certain antibiotics, have a history of heart disease, and breastfeeding women should not take this drug. Care should be taken when using this drug as various side effects may occur. Digestive symptoms such as headaches, abdominal pain, diarrhea, nausea, and vomiting have been reported, along with rare occurrences of blood abnormalities, skin rashes, liver dysfunction, and mental changes. Patients should consult a doctor immediately if these symptoms occur. Long-term use of this drug can lead to electrolyte imbalances such as hypomagnesemia, so regular testing and monitoring are necessary, especially if taken for more than one year. This drug can promote the proliferation of bacteria in the stomach by suppressing acid secretion, so if symptoms of infection like diarrhea persist, the healthcare provider should be informed. Moreover, this drug interacts with many other medications, so it is essential to discuss with a doctor or pharmacist before using it in conjunction with other medications. Caution is particularly advised when used with anticoagulants, antiviral agents, and certain antibiotics. The safety of this drug during pregnancy has not been fully established, so it should be administered cautiously under a doctor’s judgment; it is also advisable to avoid taking this drug while breastfeeding. In case of overdose, there is no specific antidote, so appropriate treatment should be provided according to symptoms, and it should be stored out of reach of children.

Serious side effects

• Angioedema, anaphylaxis reaction/shock
• Hives
• Severe allergic reactions
• Severe rashes with high fever, blistering, skin peeling, pain in mouth/eye mucous membranes
• Severe skin reactions such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), etc.
• Shortness of breath or difficulty breathing, asthma attacks, coughing+fever

Mild side effects

• Occasionally peripheral edema
• occasionally insomnia
• rarely agitation
• mental confusion
• depression
• very rarely aggression
• hallucinations
• frequent headaches
• occasionally dizziness
• sensory disturbances

This drug may be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 to 30 degrees Celsius. This will help to keep the drug's effectiveness for a long time.

Appearance

Pink circular film-coated tablet

Package unit

28 tablets (14 tablets/PTP x 2)