Simroks A Tablet

Adult dose

This medication is administered once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10mg to 10/40mg per day, with a generally recommended starting dose of 10/20mg per day. Patients who require less reduction in LDL cholesterol may start with 10/10mg once daily. After starting treatment or adjusting the dosage, blood lipids should be checked after an interval of more than 4 weeks.

This medication may cause serious muscle-related side effects, such as myopathy and rhabdomyolysis. These side effects can manifest as muscle pain, muscle tenderness, and muscle weakness, accompanied by significantly elevated creatine kinase levels in the blood. The risk is particularly heightened with high doses, so patients taking 80mg should exercise extra caution. If any unusual muscle symptoms occur, the patient must inform their physician immediately and discontinue the medication if necessary. This medication should not be used by patients with allergies to its ingredients, those with active liver disease or persistent liver function abnormalities, or women who are pregnant or breastfeeding. Additionally, the risk of myopathy increases when taken with certain powerful medications, so they should not be taken together. This medication may affect liver function; therefore, patients with abnormal liver function test results should use it with caution, and regular liver function tests are necessary during therapy. Elderly patients or those with impaired kidney function may also have an increased risk of muscle-related side effects while taking this medication and should be monitored closely. During the use of this medication, if unexplained muscle pain, weakness, or tenderness occurs, the patient must inform healthcare personnel immediately and should also notify if they are prescribed any new medications. Women of childbearing potential should avoid pregnancy while taking this medication, and should discontinue it immediately if pregnancy is confirmed. Moreover, this medication can increase blood concentration when taken with certain enzyme-inhibiting drugs, raising the risk of side effects, so patients must consult with their physician about any concomitant medications. Data regarding the safety of this medication in children and adolescents is limited, therefore it is not recommended for children under 10 years of age. There is no specific antidote for overdose; therefore, if overdose is suspected, the patient should seek appropriate treatment at a medical facility immediately.

Serious side effects

Urticaria, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, paleness, anaphylaxis, angioedema, severe skin reactions (rash, drug-induced hypersensitivity syndrome, toxic epidermal necrolysis, erythema multiforme), myopathy, rhabdomyolysis, liver abnormalities (jaundice, hepatitis, liver dysfunction, liver failure), pancreatitis, severe neurological symptoms (seizures, confusion, visual disturbances, paralysis), thrombocytopenia, respiratory problems (dyspnea

Mild side effects

Headache, diarrhea, flu-like symptoms, upper respiratory infection, muscle pain, limb pain, fatigue, nausea, abdominal pain, constipation, upper abdominal pain, vomiting, chest pain, chest discomfort, sensory decrease, sore throat, nocturia, hematuria, itching, alopecia, dizziness, insomnia, dyspepsia, mucous stool, irritable bowel syndrome, asthenia, urticaria, increased serum creatine phosphokinase (CPK), weight loss

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. Temperature should be maintained at room temperature between 1 to 30 degrees Celsius. This will help maintain the medication's effectiveness and safety over time.

Appearance

White to light yellow, double convex, rectangular tablet

Package unit

30 tablets (10 tablets/PTP x 3)