Medication info
Vystar Tablet 10/10 mg

Vystar Tablet 10/10 mg

Prescription medicationTablet경구
Ingredient · strength
Ezetimibe›10mg / 1 tabletSimvastatin›10mg / 1 tablet
Manufacturer / importer
진양제약(주)
Appearance
White to light yellow, bilaterally convex rectangular tablet
Packaging
30 tablets (10 tablets/PTP x 3)
Approval status
Active

MFDS item code 201601725 · Approved 2016.03.31 · Insurance code 650303460

Summary

Main use
Improvement of cholesterol and lipids in hypercholesterolemia (primary, homozygous familial) and mixed hyperlipidemia
Who takes it
Adults
Adult dose
This drug is administered once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10 mg to 10/40 mg daily, with the usual initial dose being 10/20 mg per day. Patients with less need for LDL cholesterol reduction can start with 10/10 mg daily. Dosage adjustments should be made after evaluating blood lipid levels at intervals of at least 4 weeks. For homozygous familial hypercholesterolemia patients,

Ingredients

Manufacturer
진양제약(주)

Efficacy & effects

Improvement of cholesterol and lipids in hypercholesterolemia (primary, homozygous familial) and mixed hyperlipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed hyperlipidemia
  • homozygous familial hypercholesterolemia
  • atherosclerotic vascular diseases due to hypercholesterolemia
View approved original text

This drug is used as an adjunct to dietary therapy in patients with primary hypercholesterolemia and mixed hyperlipidemia, reducing elevated total cholesterol, LDL cholesterol, apolipoprotein B, and triglycerides while increasing HDL cholesterol to control blood lipid levels. Additionally, in patients with homozygous familial hypercholesterolemia, it is used as an alternative therapy when other lipid-lowering treatments are insufficient or may be combined with them. This medication must be taken along with an appropriate dietary regimen, and it is important to confirm whether there are other diseases or medications that could affect lipid levels before administration. The therapeutic effect is enhanced when used with a diet that restricts fats and cholesterol. In the event of acute coronary incidents, treatment may also begin based on lipid test results. This drug helps improve hypercholesterolemia and related cardiovascular risks.

How to take

Adult dose

This drug is administered once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10 mg to 10/40 mg daily, with the usual initial dose being 10/20 mg per day. Patients with less need for LDL cholesterol reduction can start with 10/10 mg daily. Dosage adjustments should be made after evaluating blood lipid levels at intervals of at least 4 weeks. For homozygous familial hypercholesterolemia patients,

Precautions

This drug is primarily used to lower cholesterol levels and helps reduce the risk of cardiovascular disease. The most important caution when taking this drug is related to muscle-related problems. It may cause myalgia, muscle weakness, or in severe cases, rhabdomyolysis, which is the destruction of muscle tissue. If these symptoms occur, you must notify your doctor immediately. The risk of muscle problems may increase, especially when taking high doses or in conjunction with specific medications, so you should inform your doctor or pharmacist if you are taking other medications. This drug can affect liver function, so caution is needed in patients with liver disease or abnormal liver function tests. If symptoms of liver dysfunction appear, consult a healthcare professional immediately. Women who are pregnant or breastfeeding should not take this drug. If you have plans for pregnancy or may become pregnant, you should consult with a healthcare professional before taking this drug. This drug should not be administered to patients with certain genetic disorders. For example, it must not be taken by those with lactose intolerance. Elderly patients may have a more sensitive response to this drug, so dosage adjustment and caution are necessary. During the use of this drug, it is advisable to regularly check blood tests for liver function and muscle enzyme levels. Additionally, this drug can interact with multiple medications, so make sure to consult your healthcare provider when starting or stopping any new medications. Lastly, if you experience unexplained muscle pain or weakness, or signs of liver dysfunction while taking this drug, you should seek medical attention immediately.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema, myopathy, rhabdomyolysis, anaphylaxis, severe edema, severe allergic reactions, significant swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe skin reactions, severe rash, blisters, skin peeling, mucosal pain in mouth/eyes, respiratory issues, difficulty breathing or shortness of breath, asthma attacks, cough associated with fever respiratory issues, liver dysfunction (jaundice), skin or eye yellowing

Mild side effects

Headache, diarrhea, influenza, upper respiratory infection, myalgia, limb pain, fatigue, abdominal pain, sensory abnormalities, depression, nausea, dizziness, vomiting, constipation, upper abdominal pain, chest pain, chest discomfort, asthenia, sensory loss, cough, nocturia, hematuria, pruritus, edema, thirst, facial edema, syncope, insomnia, gastritis, atrophic gastritis, dyspepsia, mucus in stool, irritable bowel syndrome, sore throat, alopecia, various skin changes (nodules, pigmentation

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly closed container to protect it from air and moisture. Also, the medication should be kept at room temperature, between 1 to 30 degrees Celsius, avoiding excessively hot or cold places.

Appearance and packaging

Appearance

White to light yellow, bilaterally convex rectangular tablet

Package unit

30 tablets (10 tablets/PTP x 3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.