VYROUJEONG 10/10 mg

Adult dose

This medication is administered once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10 mg to 10/40 mg daily, with an initial recommended dose typically being 10/20 mg daily. For patients who do not require significant reductions in LDL cholesterol, treatment may begin at 10/10 mg daily. The recommended dosage for patients with homozygous familial hypercholesterolemia is 10/40 mg daily, administered once in the evening.

This medication may cause muscle-related side effects such as myopathy and rhabdomyolysis; therefore, if symptoms like muscle pain or weakness occur, consult a doctor immediately. This medication should not be used by those with hypersensitivity to its components, active liver disease patients, or during pregnancy and lactation. Especially during pregnancy, it can interfere with cholesterol biosynthesis essential for normal fetal development, so it should be discontinued immediately upon confirmation of pregnancy. This medication should not be taken in conjunction with certain potent CYP3A4 inhibitors, gemfibrozil, cyclosporine, or danazol as they increase the risk of myopathy. Additionally, patients who are genetically unable to digest lactose should avoid this medication. Patients with severe myasthenia gravis or ocular myasthenia should use this medication cautiously, and treatment should be discontinued if symptoms worsen. Liver function abnormalities may occur during treatment with this medication; therefore, patients with a history of liver disease or symptoms should undergo regular liver function tests. Due to numerous drug interactions, if taking other medications, be sure to inform your physician or pharmacist and exercise caution. This medication is also available for elderly patients; however, some elderly may be more sensitive to side effects, so caution is warranted. Women of childbearing potential should use appropriate contraceptive methods during treatment to avoid pregnancy and consult their physician if planning pregnancy. Nursing mothers should discontinue breastfeeding when taking this medication, and safety in children and adolescents has not been sufficiently confirmed, so it should be used cautiously. In the event of overdose, specific antidotes are unavailable; general treatment will be provided based on symptoms. Any unexplained muscle pain, weakness, tenderness, etc., during the course of this medication should be reported to a physician immediately, and regular check-ups and monitoring are necessary.

Serious side effects

Urticaria, angioedema, rash, anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), erythema multiforme, severe allergic reactions, severe skin adverse reactions, myopathy/rhabdomyolysis, elevated creatine kinase (CK), severe edema, hepatitis, jaundice, generalized malaise, acute renal failure, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis

Mild side effects

• Headache
• diarrhea
• influenza
• upper respiratory infection
• muscle pain
• limb pain
• fatigue
• nausea
• abdominal pain
• constipation

This medication should be stored in a tightly sealed container to protect it from exposure to air or moisture. It is also important to maintain room temperature between 1°C to 30°C when storing the medication. This helps to safely preserve the effectiveness of the medication for a longer time.

Appearance

White to pale yellow double convex rectangular tablet

Package unit

30 tablets ((10 tablets/Alu-Alu) x 3)