Cricox Capsule 400 mg (Celecoxib)

Adult dosage

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be taken with or without food. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or 100 mg per dose divided into 2 doses daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, other treatment options should be considered. Acute pain and primary dysmenorrhea The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may pose a risk of gastrointestinal bleeding for individuals who regularly consume more than three drinks a day, so it is essential to consult with a doctor or pharmacist. It can increase the risk of cardiovascular diseases, leading to serious problems such as myocardial infarction or stroke, so it is important to use the minimum effective dose for the shortest period possible. Severe gastrointestinal issues such as perforation, ulcers, and bleeding can occur, especially for elderly patients or those with a history of gastrointestinal diseases, so caution is warranted. Patients with a history of hypersensitivity or allergies, severe liver or kidney dysfunction, or active peptic ulcer disease should not take this medication. Patients with compromised liver or kidney function, asthma, heart failure, or hypertension should consult a doctor for careful use. This medication can cause various side effects, such as dyspepsia, headache, dizziness, skin rash, and cardiovascular symptoms; any abnormal symptoms should be reported to a healthcare professional immediately. Regular blood tests, liver function tests, and kidney function tests should be performed during treatment to check for abnormalities. There are many interactions with other medications, especially with antihypertensives, anticoagulants, antidepressants, and lithium, so it is important to inform the doctor of any concurrent medications. It is safest for pregnant women or those who might become pregnant, as well as nursing mothers, to avoid this medication; women planning to become pregnant should consult a doctor before use. Children and adolescents should not use this medication as its safety and efficacy have not been established, and elderly patients should be particularly monitored due to the high likelihood of decreased kidney and liver function. In the event of overdose, symptoms such as vomiting, lethargy, and respiratory depression may occur, necessitating immediate medical attention. This medication should be kept out of reach of children and should not be transferred to other containers for quality maintenance.

Gastrointestinal bleeding, cardiovascular thromboembolic response, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste distortion, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, leg cramps, hypertension, sensory decrease, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, angioedema, loss of appetite, increased appetite, depression, neurogenic hypersensitivity, drowsiness, fatal intracranial hemorrhage, hallucinations, epilepsy exacerbation, upper respiratory tract infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, breast fibroadenomatosis, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cyst, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, increased ALT, increased AST, elevated γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, synovial bursa, arthralgia, arthropathy, skeletal anomalies, myalgia, cervical tension, synovitis, tendinitis, myositis, fracture, tendon rupture, pain in the limbs, muscle rigidity, decreased hematocrit, increased hemoglobin, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reactions, skin nodules, blurred vision, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, microangiopathic glomerulonephritis, menstrual disorders, chest pain, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized bullous fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, menstrual disorders

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is best to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance

A white hard capsule filled with white to pale yellow powder with green stripes on the top and bottom.

Package unit

30 capsules/bottle