Medication info
Pletal Sustained Release Capsule 200 mg (Cilostazol)

Pletal Sustained Release Capsule 200 mg (Cilostazol)

Prescription medicationOral
Ingredient · strength
Cilostazol Micronized›200mg / 1 capsule
Manufacturer / importer
Otsuka Pharmaceutical Co., Ltd. (Korea)
Appearance
A hard capsule with a white sustained-release granule inside, consisting of a white upper and lower part.
Packaging
30 capsules/bottle, 200 capsules/bottle
Approval status
Active

MFDS item code 201601537 · Approved 2016.03.16 · Insurance code 649900430

Summary

Main use
Prevention of recurrent cerebral infarction; improvement of ischemic symptoms (e.g., pain and coldness) in chronic arterial occlusive disease
Who takes it
Adults
Adult dose
The usual adult dose is 200mg of cilostazol orally once daily. Take this medicine on an empty stomach, avoiding meals.

Ingredients

Manufacturer
Otsuka Pharmaceutical Co., Ltd. (Korea)

Efficacy & effects

Prevention of recurrent cerebral infarction; improvement of ischemic symptoms (e.g., pain and coldness) in chronic arterial occlusive disease

  • Chronic arterial occlusion
  • ulcer
  • pain
  • coldness
  • ischemic symptoms
  • cerebral infarction
View approved original text

This medication is used to improve ischemic symptoms such as ulcers, pain, and coldness caused by chronic arterial occlusion. Additionally, it helps prevent recurrence after cerebral infarction. It is effective in improving blood circulation and maintaining cerebral vascular health.

How to take

Adult dose

The usual adult dose is 200mg of cilostazol orally once daily. Take this medicine on an empty stomach, avoiding meals.

Precautions

This medication may increase heart rate, leading to angina symptoms, so symptoms such as chest pain should be carefully monitored. Patients at high risk of bleeding or those with recent hemorrhagic diseases should not use this medication. Patients with heart failure or allergies to this medication's ingredients, and women who are pregnant or breastfeeding should also avoid use. Careful monitoring for bleeding is necessary when used with medications that increase bleeding risk, such as anticoagulants or antiplatelet drugs. Women who are menstruating should be cautious due to the risk of bleeding. Patients with severely impaired renal or liver function, diabetes, hypertension, or cardiac rhythm disorders should be administered with caution. This medication may cause various side effects such as headaches, diarrhea, palpitations, and joint pain, so if unusual symptoms occur, consult a doctor immediately. Especially if bleeding symptoms or heart-related symptoms arise, treatment should be stopped immediately, and appropriate care should be received. This medication may cause dizziness, so care is needed when driving or operating machinery. Taking it with food may increase drug concentration, so it is recommended to take it on an empty stomach. Co-administration with specific medications may increase drug concentration or enhance effects, so inform your doctor of any ongoing treatments. Pregnant women or those who could become pregnant should not take this medication, and those who are breastfeeding should stop nursing. Children and the elderly may have different bodily functions, so special caution is needed when administering.

Side effects

  • Headache
  • diarrhea
  • atrial fibrillation
  • palpitations
  • joint swelling
  • limb pain
  • chest discomfort
  • tendency to bleed
  • intracerebral hemorrhage
  • pulmonary hemorrhage
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  • subcutaneous hemorrhage
  • gastrointestinal bleeding
  • nosebleed
  • fundal bleeding
  • hematuria
  • pancytopenia
  • agranulocytosis
  • thrombocytopenia
  • leukopenia
  • aplastic anemia
  • fever
  • cough
  • dyspnea
  • abnormal chest X-ray
  • eosinophilia
  • congestive heart failure
  • myocardial infarction
  • angina
  • ventricular tachycardia
  • jaundice
  • AST elevation
  • ALT elevation
  • ALP elevation
  • LDH elevation
  • phototoxic reaction
  • rash
  • urticaria
  • itching
  • back pain
  • infection
  • chills
  • malaise
  • neck stiffness
  • pelvic pain
  • retroperitoneal hemorrhage
  • atrial flutter
  • loss of rhythm tachycardia
  • ventricular tachycardia
  • loss of rhythm extrasystole
  • ventricular extrasystole
  • hypotension
  • orthostatic hypotension
  • palpitations
  • tachycardia
  • flushing
  • hypertension
  • anxiety
  • neuralgia
  • weakness
  • strange dreams
  • heavy head
  • dizziness
  • insomnia
  • paresthesia
  • drowsiness
  • tremor
  • abnormal stool
  • dyspepsia
  • cholelithiasis
  • colitis
  • duodenal ulcer
  • duodenitis
  • esophagitis
  • γ-GTP elevation
  • gastritis
  • gastroenteritis
  • gum bleeding
  • black stools
  • digestive ulcers
  • periodontal abscess
  • gastric ulcer
  • tongue swelling
  • abdominal pain
  • nausea
  • vomiting
  • loss of appetite
  • heartburn
  • abdominal distension
  • erythrocytosis
  • purpura
  • prolonged bleeding time
  • thrombocytosis
  • eosinophilia
  • anemia
  • facial swelling
  • peripheral edema
  • gout
  • hyperlipidemia
  • elevated blood glucose
  • myalgia
  • arthralgia
  • bone pain
  • bursitis
  • increased cough
  • pharyngitis
  • rhinitis
  • asthma
  • sinusitis
  • pneumonia
  • diabetes
  • dry skin
  • boil
  • skin thickening
  • amblyopia
  • blindness
  • diplopia
  • ear pain
  • tinnitus
  • conjunctivitis
  • proteinuria
  • cystitis
  • vaginal bleeding
  • vaginitis
  • urinary frequency
  • renal failure
  • renal impairment
  • BUN elevation
  • creatinine elevation
  • uric acid elevation
  • sweating
  • edema
  • chest pain
  • pain
  • fatigue
  • fever
  • sensory loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance and packaging

Appearance

A hard capsule with a white sustained-release granule inside, consisting of a white upper and lower part.

Package unit

30 capsules/bottle, 200 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.