Esomeprazole Magnesium 40 mg Tablets (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and must not be chewed or crushed. 1. Adults 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: Administer 40 mg once daily for 4 weeks. If symptoms persist, an additional 4 weeks of treatment is recommended. - Long-term maintenance therapy for prevention of recurrence of esophagitis: Administer 20 mg once daily. - Symptomatic treatment for gastroesophageal reflux disease without esophagitis:

Children's dosage

Adolescents aged 12 years and older. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: Administer 40 mg once daily for 4 weeks. If symptoms persist, an additional 4 weeks of treatment is recommended. - Treatment of symptoms of gastroesophageal reflux disease without esophagitis:

This medication should not be used in certain patients. For example, it should not be administered to patients allergic to this medication or its components, or who have had hypersensitivity reactions to benzimidazoles. Patients allergic to penicillin or macrolide antibiotics among the antibiotics used for eradication of Helicobacter pylori should also avoid using this drug. Patients taking certain medications that may pose risks when combined with this drug, such as terfenadine, cisapride, pimozide, astemizole, atazanavir, nelfinavir, or rilpivirine-containing medications, should not be treated with this drug. It is also safer for breastfeeding women not to take this medication. Patients with a history of myocardial infarction should avoid using this medication. This drug may cause various side effects such as headache, abdominal pain, diarrhea, nausea, vomiting, skin rash, myalgia, and hypomagnesemia. Special attention is required if hypomagnesemia occurs due to the risk of serious electrolyte abnormalities or arrhythmias. Regular monitoring is needed during prolonged use, and there may be a slightly increased risk of gastrointestinal infections. This medication may also interact with other drugs, so if taking other medications, consult with a doctor or pharmacist. Due to limited safety data on this drug during pregnancy, it should be used with caution, and it is advised not to use during breastfeeding. In case of overdose, as there are no specific antidotes, appropriate treatment according to symptoms is required, and it should be kept out of reach of children.

Serious side effects

Urticaria, angioedema, anaphylaxis, shock, jaundice, hepatitis, liver failure, severe cutaneous adverse reactions (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, severe edema, severe allergic reactions, severe skin adverse reactions, respiratory distress, asthma attacks, chest pain, acute generalized exanthematous pustulosis.

Mild side effects

Headache, dizziness, sensory disturbance, drowsiness, taste disturbance, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, elevated liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, interstitial nephritis, gynecomastia, asthenia, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, back pain, chest pain.

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, at a temperature between 1°C and 30°C. Such storage maintains the effectiveness of the medication and prevents degradation.

Appearance

Pink round enteric-coated film-coated tablets

Package unit

28 tablets/box [28 tablets (14 tablets/Alu-Alu*2)]