Jobatorin Tablet 10/20 mg (Ezetimibe / Simvastatin)

Adult dose

This medication should be taken once daily in the evening, regardless of meals. For patients with primary hypercholesterolemia, the dosage range is 10/10 mg to 10/40 mg per day, and the generally recommended initial dose is 10/20 mg daily. Patients with less need for LDL cholesterol reduction may start at 10/10 mg daily. Lipid levels in the blood should be checked at least 4 weeks after initiating treatment or adjusting the dosage.

This medication is used to lower cholesterol levels in the blood. Caution is required as muscle-related problems such as myalgia or muscle weakness may occur when taking this medication. In particular, the risk of muscle damage may be higher when taken in high doses, so consult a physician immediately if any abnormal symptoms arise. Patients with liver dysfunction or liver disease should avoid taking this medication. Pregnant or nursing women should also not use this medication. Furthermore, this medication may interact with other drugs, so it is essential to inform healthcare providers about any medications currently being taken. Especially, taking it with certain antibiotics, antifungals, immunosuppressants, or antivirals may increase the risk of muscle damage. It is advisable to regularly monitor liver function and muscle enzyme levels through blood tests while taking this medication. Elderly patients may respond more sensitively to this medication, so caution is necessary during use. Lastly, immediately inform a physician if unexplained muscle pain or weakness occurs during treatment, and do not discontinue the medication without following the healthcare provider's instructions.

Serious side effects

Urticaria, angioedema, rash, anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), erythema multiforme, hepatitis, liver abnormalities (jaundice), pancreatitis, severe allergic reactions, severe skin reactions, myopathy, rhabdomyolysis, severe edema, acute renal failure due to myopathy/rhabdomyolysis, severe neurological symptoms (e.g., mental disturbance, confusion, visual abnormalities, paralysis)

Mild side effects

Headache, diarrhea, influenza, upper respiratory infection, myalgia, limb pain, fatigue, abdominal pain, pharyngitis, sinusitis, arthralgia, low back pain, cough, weakness, cataracts, constipation, dyspepsia, flatulence, nausea, eczema, itching, rash, dizziness, sensory disturbances, depression, cholelithiasis, cholecystitis, eosinophilia, thrombocytopenia, vomiting, pancreatitis, urticaria, increased serum creatine phosphokinase (CPK), weight loss, edema

This medication is sensitive to air and moisture, so it should be stored in a sealed container. It is best to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance

White to off-white, bilaterally convex, rectangular tablet

Package unit

30 Tablets (10 Tablets/ Blister Pack x 3)