Cretrol 10/10 mg

Adult dose

This medication is taken once daily, regardless of meals. For primary hypercholesterolemia, dosing may start at 10/5 mg daily and can be increased up to 10/20 mg. The recommended initial dose is 10/5 mg per day. For patients requiring more reduction of LDL cholesterol, the dosage may be adjusted accordingly. Blood lipid levels should be monitored with intervals of at least 4 weeks after starting medication or adjusting the dose.

This medication can rarely cause rhabdomyolysis, resulting in severe kidney problems due to muscle tissue damage; thus, if serious muscle pain or weakness occurs, consult a physician immediately. This medication should not be taken by specific patients, such as those with liver diseases, muscular diseases, severely impaired kidney function, pregnant women, or breastfeeding women. Caution should be exercised in those at high risk for muscle damage, such as alcoholics, patients with liver dysfunction, and the elderly, and regular blood tests are needed to monitor muscle and liver function. This drug may increase liver enzyme levels, and if symptoms of liver damage (e.g., fatigue, jaundice, abdominal pain) occur, healthcare personnel should be notified immediately. If symptoms such as muscle pain, muscle weakness, fatigue, fever occur while taking this medication, inform a doctor immediately and undergo necessary testing. This medication may interact with other drugs, so inform your doctor or pharmacist if you are taking other medications. Women who are pregnant or planning to become pregnant should not take this drug, and if pregnancy is confirmed during treatment, it should be stopped immediately, and appropriate contraception should be used. Safety in children and adolescents has not been adequately established, so it is not recommended. Elderly patients should take caution due to the higher risk of muscle damage, and consultation with healthcare professionals is necessary if there are abnormalities in liver or kidney function. This drug contains lactose, so patients with lactose intolerance should not take it. During treatment, it is crucial to undergo regular liver function tests and muscle enzyme tests, and consult healthcare professionals if any abnormal symptoms arise. Caution is advised when driving or operating machinery, as symptoms such as dizziness may occur.

Serious side effects

Hives, swelling, tightness in the chest, difficulty breathing, cold sweat, pallor, severe allergic reaction, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of the mouth/eyes, severe skin reactions, difficulty or shortness of breath, asthma attacks, abnormal respiratory issues accompanied by cough and fever, jaundice, liver abnormalities, sudden and severe headache, lightning-like headache, seizures, confusion, visual disturbances, paralysis, serious neurological symptoms

Mild side effects

• Pharyngitis
• arthralgia
• headache
• dizziness
• upper respiratory infection
• myalgia
• edema
• elevated serum bilirubin
• acne-like dermatitis
• pruritus

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain storage temperature between 1 and 30 degrees Celsius at room temperature to ensure prolonged effectiveness and safety of the drug.

Appearance

White to nearly white round film-coated tablet

Package unit

Blister - 30 tablets/blister [10 tablets/blister × 3], Bottle - 30 tablets/bottle, Bottle - 300 tablets/bottle