Dulorban Tablet 10/20 mg (Ezetimibe, Rosuvastatin Calcium)

Adult dose

This medication is administered once daily without regard to meals. For primary hypercholesterolemia, the dosage range is between 10/5 mg to 10/20 mg once daily. A starting dose of 10/5 mg once daily is recommended. For patients requiring further reduction in LDL-cholesterol, the dosage may be adjusted. After initiation of therapy or dosage adjustment, lipid levels should be checked after an interval of more than 4 weeks.

This medication contains two components: rosuvastatin and ezetimibe. Several precautions must be followed while taking this medication. First, this medication can rarely cause severe muscle damage, known as rhabdomyolysis, which may lead to kidney function issues. Therefore, if severe muscle pain or weakness occurs, you should immediately consult a physician. Second, this medication should not be administered to individuals with specific diseases. For instance, individuals allergic to any of its components or those with liver disease, muscle disease, severe kidney dysfunction, or women who are pregnant or breastfeeding should not take this medication. Third, individuals with alcohol dependence, poor liver function, elderly patients, those with hypothyroidism, or those with a history of muscle-related drug side effects should use this medication cautiously and regularly check blood tests and muscle conditions as instructed by their doctors. Fourth, side effects like liver dysfunction, muscle pain, headache, indigestion may occur during the course of taking this medication, so any symptoms should prompt consultation with healthcare providers. Fifth, there may be interactions with other medications, so inform your doctor or pharmacist of any other medications you are taking, especially if you are using anticoagulants, fibrates, or cyclosporine, as caution is needed in these cases. Sixth, pregnant women or those planning to become pregnant should not take this medication, and if pregnancy is confirmed while on this medication, it should be discontinued immediately and consult a doctor. Finally, children, adolescents, elderly patients, and those with impaired liver or kidney function must always consult with a specialist before taking this medication and adhere strictly to the prescribed dosages and regimens. This medication requires regular testing and close monitoring before and during treatment. Therefore, follow your doctor's directions closely and report any unusual symptoms immediately.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headaches, lightning headaches, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Headache
• nasopharyngitis
• arthralgia
• dizziness
• fatigue
• abdominal pain
• diarrhea
• constipation
• nausea
• pruritus

This medication must be stored in a tightly closed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White to almost white, round film-coated tablets

Package unit

30 tablets (10 tablets/Alu-Alu x 3)