Credable Tablet 10/10 mg (Ezetimibe, Rosuvastatin Calcium)

Adult dose

This medication is administered once daily, regardless of meals. For the treatment of primary hypercholesterolemia, the initial dose is 10/5 mg once daily, and the dose can be adjusted between 10/5 mg and 10/20 mg as needed. Cholesterol levels should be checked at intervals of more than 4 weeks after dose adjustment to decide on dose escalation. The maximum dose is 10/20 mg once daily.

This medication may cause serious muscle problems, so any symptoms such as muscle pain or muscle weakness should be reported to a doctor immediately. Particularly, patients at high risk for serious myopathy or rhabdomyolysis should temporarily suspend or discontinue the use of this medication. It should not be used in individuals with a known allergy to the active ingredients or excipients, severe hepatic impairment, muscle diseases, severe renal failure, pregnant or potentially pregnant women, or breastfeeding mothers. Additionally, this medication contains lactose and should not be administered to patients with lactose intolerance. Caution is also advised for alcoholics or patients with a history of liver disease, severe myasthenia gravis, the elderly, and patients with diminished renal function; they should use this medication cautiously and undergo regular tests under a doctor’s supervision. This medication may affect liver function; therefore, liver function tests should be performed before administration and regularly during treatment. It may slightly increase blood glucose levels, so patients at risk for diabetes should monitor their blood glucose periodically. There may be potential interactions when taken with other drugs, so patients should inform their doctor or pharmacist of any medications they are taking. This medication is not recommended for women who are pregnant or breastfeeding, and fertile women should use appropriate contraception while taking it. Safety in children or adolescents has not been sufficiently established, so it is advisable not to use it without a doctor’s judgment. In case of overdose, as there is no specific antidote, appropriate treatment and supportive care should be provided according to symptoms, and liver function and muscle enzyme levels should be monitored. This medication should be kept out of the reach of children and should not be transferred to other containers.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory difficulties accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis,

Mild side effects

• Headache
• nasopharyngitis
• arthralgia
• dizziness
• fatigue
• abdominal pain
• diarrhea
• nausea
• pruritus
• acne-like dermatitis

This medication should be stored in a tightly sealed container to protect it from air and moisture and is best kept at a temperature between 1°C and 30°C. Proper storage will help maintain the effectiveness of the medication and prevent degradation.

Appearance

White to almost white round film-coated tablets

Package unit

30 tablets (10 tablets/PTP packaging x 3), 100 tablets/bottle