Medication info
CreaZin Plus Tablet 10/20mg

CreaZin Plus Tablet 10/20mg

Prescription medicationTablet경구
Ingredient · strength
Ezetimibe›10mg / 1 tabletRosuvastatin Calcium›20.8mg / 1 tablet
Manufacturer / importer
영진약품(주)
Appearance
White to nearly white round film-coated tablet
Packaging
30 tablets (10 tablets/blister × 3)
Approval status
Active

MFDS item code 201601206 · Approved 2016.02.29 · Insurance code 642404080

Summary

Main use
Improvement of hypercholesterolemia (primary and mixed type) and suppression of the risk of atherosclerotic vascular disease
Who takes it
Adults
Adult dose
This medication is administered once daily regardless of meals. For primary hypercholesterolemia, it is administered in the range of 10/5mg to 10/20mg daily, with an initial recommended dose of 10/5mg per day. If more significant reduction of LDL cholesterol is required, the dosage can be adjusted. After starting treatment or adjusting the dosage, blood lipid levels should be checked at intervals of at least 4 weeks, with a maximum daily dose of 10/20mg.

Ingredients

Manufacturer
영진약품(주)

Efficacy & effects

Improvement of hypercholesterolemia (primary and mixed type) and suppression of the risk of atherosclerotic vascular disease

  • Primary hypercholesterolemia
  • dyslipidemia
  • increased risk of atherosclerotic vascular disease due to hypercholesterolemia
  • diabetes
  • hypothyroidism
  • obstructive liver disease
  • chronic kidney failure
View approved original text

This medication helps lower total cholesterol, LDL cholesterol, Apo B protein, triglycerides, and non-HDL cholesterol levels, and increase HDL cholesterol levels in patients with primary hypercholesterolemia, particularly heterozygous familial and non-familial, or mixed dyslipidemia. It is mainly used as an adjunct to dietary therapy, and it is important to accompany it with appropriate dietary control, including limiting saturated fat and cholesterol intake. Furthermore, treatment is conducted considering multiple risk factors to reduce the risk of atherosclerotic vascular disease caused by hypercholesterolemia. Before taking this medication, it is recommended to identify and treat other causes that may induce dyslipidemia, such as diabetes and hypothyroidism, if necessary. During treatment, total cholesterol, LDL, HDL, and triglyceride levels should be regularly checked to evaluate effectiveness. This medication is used to lower the risk of cardiovascular disease by improving abnormal blood lipid levels.

How to take

Adult dose

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, it is administered in the range of 10/5mg to 10/20mg daily, with an initial recommended dose of 10/5mg per day. If more significant reduction of LDL cholesterol is required, the dosage can be adjusted. After starting treatment or adjusting the dosage, blood lipid levels should be checked at intervals of at least 4 weeks, with a maximum daily dose of 10/20mg.

Precautions

This medication can rarely cause severe damage to muscle tissue, leading to renal function issues, so if symptoms of muscle pain or weakness appear, consult a doctor immediately. This medication may affect liver function, so it should not be administered to patients with liver disease or elevated liver enzyme levels, and liver function tests should be conducted regularly during treatment. It is safer not to use this medication in patients with certain genetic disorders, liver, or kidney diseases, and pregnant or breastfeeding women should also avoid its use. Elderly patients, those with a history of alcoholism, and patients with hypothyroidism who have a higher risk of myopathy should use this medication with caution and undergo regular check-ups as directed by a doctor. This medication may interact with other drugs, so patients should inform healthcare providers about any other medications they are taking, especially if combining with anticoagulants or specific antibiotics and antifungals. During the course of this medication, if severe muscle pain, muscle cramps, fatigue, fever, or similar symptoms occur, immediately notify healthcare providers and undergo examination. This medication may cause dizziness when driving or operating machinery, so caution is advised during these activities. It is recommended not to use this medication in children, as safety and efficacy have not been established. This medication must be taken according to a physician's prescription and instructions, and it should be stored out of reach of children.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities associated with cough + fever, yellowing of the skin or eyes (jaundice), severe lethargy throughout the body, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination problems.

Mild side effects

  • Nasopharyngitis
  • arthralgia
  • headache
  • dizziness
  • upper respiratory tract infection
  • myalgia
  • itching
  • rash
  • pruritus
  • nausea
Show 27 more
  • abdominal pain
  • diarrhea
  • fatigue
  • numbness
  • paresthesia
  • chest discomfort
  • loss of appetite
  • abdominal bloating
  • syncope
  • generalized pain
  • muscle cramps
  • gout
  • erectile dysfunction
  • urticaria
  • dermatitis
  • skin burning sensation
  • alopecia
  • oropharyngeal pain
  • nasal congestion
  • cough
  • drowsiness
  • neurodegenerative disorders
  • orthostatic dizziness
  • migraine
  • bronchitis
  • rhinitis
  • etc.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture and should be kept at room temperature between 1 to 30 degrees Celsius. Proper storage will maintain the medication's effectiveness and prevent deterioration.

Appearance and packaging

Appearance

White to nearly white round film-coated tablet

Package unit

30 tablets (10 tablets/blister × 3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.