Eshuba Tablets 10/20 mg (Ezetimibe, Rosuvastatin)

Adult dose

This drug is administered once daily regardless of meals. For primary hypercholesterolemia, an initial dose of 10/5 mg daily is recommended. In patients requiring further LDL cholesterol reduction, the dosage may be adjusted. After initiation of therapy or dosage adjustment, the patient's blood lipid levels should be checked at intervals of more than 4 weeks to adjust the dosage, and the daily maximum may be increased to 10/20 mg.

This drug may cause adverse reactions in the muscles; therefore, if symptoms of severe muscle pain or weakness occur, the doctor should be informed immediately. Due to the potential for acute kidney dysfunction caused by muscle damage, extra caution is needed in patients with renal disease or other risk factors. It may affect liver function; therefore, patients with liver disease or abnormally high liver enzyme levels should not use this drug or should use it cautiously. This drug should not be administered to women who are pregnant or may become pregnant, or who are breastfeeding. The safety and efficacy of this drug have not been adequately established in children or the elderly, so consultation with a specialist is required before use. It may interact with other medications, so it is essential to inform healthcare professionals of any currently taken medicines. There is no specific antidote for overdose; thus, the dosage must be strictly adhered to, and if symptoms arise, medical consultation should be sought immediately. During the use of this drug, it is crucial to undergo regular blood tests and liver function tests to check for abnormalities. Patients should avoid alcohol consumption and seek medical attention immediately if symptoms such as sudden severe muscle pain or weakness occur. This drug contains lactose; therefore, patients with lactose intolerance should avoid taking it.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough + fever, jaundice (yellowing of the skin or eyes), severe lethargy, sudden and extremely severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination changes

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• nasopharyngitis
• fatigue
• muscle pain
• rash
• itching

This drug should be stored in a tightly closed container to protect it from air and moisture. It is advisable to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Pink oval film-coated tablets

Package unit

30 tablets (10 tablets PTP x 3), 30 tablets/bottle, 100 tablets/bottle