Eshuva 10/10 mg (Ezetimibe, Rosuvastatin)

Adult dose

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, an initial dosage of 10/5 mg per day is recommended, and the dosage can be adjusted from 10/5 mg to 10/20 mg depending on the patient's condition. After adjusting the dosage, blood lipid levels should be checked at intervals of more than 4 weeks to potentially increase to a maximum of 10/20 mg per day.

This medication poses a risk of muscle-related issues, so if severe muscle pain or weakness occurs, consult a doctor immediately. In particular, in cases of severe infections, hypotension, major surgery, trauma, or serious endocrine and electrolyte disturbances, it may be necessary to temporarily stop or discontinue using this drug. It should not be used in patients with allergies to any of its components or with liver disease, muscle disease, or severe renal impairment. Women who are pregnant or possibly pregnant, or nursing mothers should also avoid using this medication. Caution must be exercised when using this drug in patients with alcohol dependence or poor liver function, elderly patients, those with hypothyroidism, or with a history of genetic muscle disorders. This medication contains lactose, so patients with lactose intolerance should refrain from taking it. During treatment, liver function and muscle condition should be monitored regularly, and immediate medical attention should be sought if liver enzyme levels are abnormally high or if severe muscle pain occurs. There should be caution regarding drug interactions when taking other medications, especially when used together with certain antibiotics, antifungals, immunosuppressants, and fibrate medications, as the risk of muscle abnormalities may increase. During pregnancy, it can be harmful to the fetus, so contraception must be ensured, and if pregnancy is confirmed, intake should be immediately discontinued. Safety in children or adolescents has not been fully established and is not recommended. In the case of overdose, there is no specific antidote, so appropriate treatment should be received based on symptoms, and liver function and muscle condition should be monitored. This drug should be kept out of the reach of children and not stored in another container.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory difficulty with cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headaches, lightning headache, seizures, confusion, visual disturbances, paralysis, urinary

Mild side effects

• Headache
• dizziness
• nasopharyngitis
• elevated ALT
• elevated AST
• elevated ALP
• abnormal liver function tests
• dizziness
• chest pain
• fatigue

This medication should be stored in a tightly closed container to prevent air and moisture from entering, and the storage temperature should be kept between 1°C and 30°C (room temperature). Storing it this way can help maintain the drug's efficacy.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets (10 tablets PTP x 3), 30 tablets/bottle, 100 tablets/bottle