Ezrosu 10/5 mg

Adult dose

This drug is administered once daily, irrespective of meals. For primary hypercholesterolemia, an initial dose of 10/5 mg once daily is recommended. The dosage range is from 10/5 mg to 10/20 mg daily, and if patients require more reduction in LDL cholesterol, the dose may be adjusted accordingly. Blood lipid levels should be checked at intervals of more than four weeks after starting administration or adjusting the dose.

This drug poses a risk of serious problems in muscles, so if symptoms such as muscle pain or weakness occur, notify a physician immediately. In particular, if there are severe infections, low blood pressure, major surgery, trauma, or metabolic disorders, this drug may need to be temporarily discontinued or stopped. Patients with allergies to this drug, severely impaired liver function, muscle diseases, certain kidney function impairments, pregnant or nursing women should not be administered this drug. In addition, patients at high risk of myopathy should use this drug with caution and require regular monitoring of muscle enzyme levels. Liver function tests should be conducted before starting this drug and should be repeated if abnormalities occur during treatment. This drug should be administered with caution in patients with a history of alcoholism or liver disease, and the risk of side effects may increase due to drug interactions, so any other medications being taken must be reported. Women who are pregnant or may become pregnant should use appropriate contraception while taking this drug and must stop taking it immediately upon confirming pregnancy. This medication has not been established for safety and effectiveness in children and is not recommended. Elderly patients may be at risk for myopathy, so caution is needed, but dose adjustment is generally not required. In the case of overdose, there is no specific antidote; appropriate treatment and liver function and muscle enzyme tests are required based on symptoms. Store this medication out of reach of children, and do not transfer it to another container.

Serious side effects

Hives, swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, severe rashes with high fever, blisters, pain in mucous membranes of mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, respiratory problems, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and severe symptoms

Mild side effects

• Headache
• dizziness
• nasopharyngitis
• ALT elevation
• AST elevation
• ALP elevation
• abnormal liver function tests
• dizziness
• chest pain
• fatigue

This drug is sensitive to air and moisture, so it must be stored in a tightly closed container. The storage temperature is best maintained at room temperature between 1 degree and 30 degrees. Storing it this way can help maintain the drug’s effectiveness for a long time.

Appearance

White rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle, 30 tablets/box [10 tablets/PTP x 3]