Rabeplus Tablets 20mg (Rabeprazole Sodium)

Adult dose

Gastric ulcer, duodenal ulcer: For adults, administer Rabeprazole Sodium 10 mg orally once daily. Depending on symptoms, this may be increased to 20 mg orally once daily. Generally, gastric ulcers are treated for up to 8 weeks, and duodenal ulcers for up to 6 weeks. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If symptoms persist after 8 weeks of a proton pump inhibitor (PPI), it may be increased additionally to 10 mg or 20 mg taken orally twice daily for another 8 weeks considering patient condition. However, the 20 mg twice daily dosage is only applicable in patients with verified severe mucosal damage. Symptom relief of gastroesophageal reflux disease: Administer 10 mg once daily. If symptoms do not improve after 4 weeks, further medical evaluation is needed. After symptom resolution, on-demand therapy with 10 mg once daily can be used to manage any symptoms that may appear later. Long-term maintenance therapy of gastroesophageal reflux disease: Administer 10 mg or 20 mg orally once daily depending on the patient. Helicobacter pylori eradication: Patients with Helicobacter pylori infection should be treated with eradication therapy. It is recommended to co-administer this medication 20 mg with Clarithromycin 500 mg and Amoxicillin 1 g twice daily for 7 days. Zollinger-Ellison syndrome: The recommended initial dose for adults is 60 mg once daily. The dose may be adjusted to a maximum of 120 mg daily according to individual patient needs. Doses up to 100 mg may be administered once daily, while the 120 mg dose should be divided into twice daily doses of 60 mg. Patients with Zollinger-Ellison syndrome have been treated with this medication for up to 1 year. Patients with liver impairment: Adverse reactions of hepatic encephalopathy have been reported in cirrhosis patients; therefore, caution is required. Children: Safety for children has not been established. Elderly: Caution is advised as liver function may often be impaired.

This medication should not be used in patients who are allergic to this medication or its components or have had hypersensitivity reactions. Additionally, it is recommended not to administer it to patients taking certain antibiotics or other medications, or to pregnant or breastfeeding women for safety precautions. Patients with compromised liver function, elderly individuals, or those with a history of drug allergies should be particularly careful when using this medication. If symptoms of an allergy such as rash, hives, or itching occur during treatment, the medication should be discontinued immediately. Regular blood tests and liver function tests should be conducted, and if any abnormal symptoms are noted, the doctor should be consulted for appropriate actions. Various side effects may occur in different areas including heart, gastrointestinal, nervous, respiratory, and skin, so symptoms should be closely monitored. Caution is particularly necessary for increased fracture risk with long-term use of this medication. This medication can interact with other drugs, so it is essential to inform the doctor or pharmacist of any medications being taken. It is safer not to use this medication during pregnancy or breastfeeding. Caution is required as drowsiness may occur while driving or operating machinery. This medication should not be chewed or crushed and must be swallowed whole; it should be stored out of reach of children. If this medication is to be used long-term, it is important to regularly check the health status through examinations.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory problems accompanied by cough + fever, skin or eyes turning yellow (jaundice), extreme lethargy, sudden and very severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination.

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechiae

This medication may be sensitive to air and moisture, so it should definitely be stored in a sealed container. The recommended storage temperature is between 1 degree Celsius and 30 degrees Celsius. This will help maintain the medication's effectiveness for a longer period.

Appearance

Pale yellow, round enteric-coated tablet

Package unit

28 tablets (14 tablets/AluAlu packaging × 2)