Atorine Tablets 10 mg (Atorvastatin Calcium Trihydrate)

Adult dosage

For the treatment of hyperlipidemia, the recommended starting dose is 10 mg of atorvastatin once daily. For patients requiring more significant reductions in LDL cholesterol levels, the starting dose can be 20 mg or 40 mg once daily. The dosage range is 10 to 80 mg once daily. After initiating treatment and adjusting the dosage, lipid levels should be analyzed within 2-4 weeks for further dosage adjustments. The goal of treatment is to lower LDL cholesterol levels; therefore, LDL cholesterol is recommended for assessing treatment initiation and response. If LDL cholesterol levels cannot be used, total cholesterol levels should be monitored to gauge treatment response. For patients with homozygous familial hypercholesterolemia, the treatment dosage is 10 to 80 mg once daily, given in conjunction with other lipid-lowering therapies (e.g., LDL apheresis) or when such therapies are not possible.

Children's dosage

The recommended starting dose for pediatric patients (10-17 years) with heterozygous familial hypercholesterolemia is 10 mg once daily, with a maximum recommended dose of 20 mg once daily. The dosage should be adjusted at intervals of four weeks or more.

This medication may pose a risk of muscle problems; therefore, if symptoms of muscle pain or weakness occur, immediate discontinuation and consultation with a physician are required. This medication should not be used in women with certain conditions, during pregnancy, during breastfeeding, or in children under 10 years of age. Patients with liver or kidney function issues should use this medication with caution, and regular monitoring of liver function and muscle condition is important. Interactions may occur when taken with other medications, so patients should inform their doctor or pharmacist of any medications they are currently taking. It is recommended to avoid or limit alcohol intake during the medication course, and excessive grapefruit juice should also be avoided. Women who may become pregnant should use appropriate contraceptive methods while taking this medication, and if pregnancy is confirmed, the medication should be discontinued immediately. Women who are breastfeeding should not take this medication, and special caution is needed for children and older adults when using this medication. There is no specific antidote for overdose, so in case of overdosage, it is essential to visit a medical institution immediately for treatment based on symptoms. Keep this medication out of reach of children, and it is safest to store it in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, jaundice (yellowing of skin or eyes), profound lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination issues

Mild side effects

• Fatigue
• malaise
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, it should be kept in a temperature range of 1 to 30 degrees Celsius, avoiding excessively hot or cold places.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle