Basta Tablet 10/20 (Ezetimibe, Simvastatin)

Adult dose

This medication should be taken once daily in the evening, regardless of meals. For patients with primary hypercholesterolemia, the dosing range is from 10/10mg to 10/40mg per day, and the generally recommended initial dose is 10/20mg daily. Patients with less need for LDL cholesterol reduction may start with 10/10mg per day. Lipid levels should be checked at intervals of more than 4 weeks after starting or adjusting the dosage.

This medication is primarily used to lower blood cholesterol levels and reduce the risk of cardiovascular disease. Care should be taken for muscle-related adverse symptoms such as muscle pain or weakness while taking this medication; if such symptoms occur, consult a physician immediately. The risk of serious muscle damage, including myopathy or rhabdomyolysis, increases particularly when taken at high doses or in conjunction with certain medications. Patients with active liver disease or abnormally high liver enzyme levels should not take this medication. Women who are pregnant or breastfeeding should also avoid this medication, and women of childbearing age should only take it after confirming the possibility of pregnancy. This medication should not be taken with strong CYP3A4 inhibitors such as specific antifungal agents, antibiotics, or antiviral medications, due to increased risk of side effects. Furthermore, it should also be avoided in combination with medications like gemfibrozil, cyclosporine, danazol, and fusidic acid. Caution is necessary for elderly patients, those with decreased kidney function, and patients with hypothyroidism while taking this medication. Regular monitoring of liver function and muscle condition during treatment is recommended, and any adverse symptoms should be reported to healthcare professionals immediately. This medication contains lactose, and patients with lactose intolerance should not take it. Lastly, it is crucial to inform healthcare providers about this medication when being prescribed new drugs during treatment.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, breathlessness or difficulty breathing, asthma attack, respiratory distress with cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination problems

Mild side effects

• Headache
• diarrhea
• influenza-like symptoms
• upper respiratory tract infection
• muscle pain
• limb pain
• fatigue
• abdominal pain
• nausea
• constipation

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent degradation.

Appearance

White to off-white, biconvex rectangular tablet

Package unit

30 tablets (10 tablets/PTP × 3)