Alopergil Tablets 5mg (Donepezil Hydrochloride Monohydrate)

Adult dose

As Donepezil Hydrochloride, administer 5 mg once daily before bedtime. If unusual dreams, nightmares, or insomnia occur, consider administering in the morning. Normal concentration of Donepezil is reached 15 days after administration, so for 4-6 weeks, administer the 5 mg dose. After evaluating clinical response, it may be increased up to 10 mg. When increasing to 10 mg per day, pay attention to gastrointestinal adverse reactions.

Child dose

There is no experience in using this drug in children.

This medication is used for the treatment of Alzheimer's dementia with Donepezil Hydrochloride Monohydrate as the main ingredient. This medication should not be used in patients who are allergic to certain components, pregnant or breastfeeding women, and patients with genetic issues such as lactose intolerance. Patients with a history of heart diseases or peptic ulcers, patients with a history of asthma or chronic obstructive pulmonary disease, and patients with extrapyramidal disorders such as Parkinson's disease should use this medication cautiously. This medication can cause serious side effects such as slow heart rate, arrhythmia, gastrointestinal bleeding, liver dysfunction, cerebrovascular disorders, and motor function disorders, so if any unusual symptoms occur, you should consult a healthcare professional immediately. Some patients may experience side effects such as nausea, vomiting, diarrhea, loss of appetite, dizziness, insomnia, headache, and fatigue, and these symptoms are usually temporary. This medication should only be used in patients with a definitive diagnosis of Alzheimer's disease, and if no therapeutic effect is observed, discontinuation should be considered. Patients with cardiovascular diseases may experience cardiac-related reactions such as bradycardia or heart block, so regular ECG monitoring may be necessary. This medication increases gastric acid secretion and enhances gastrointestinal motility, which may worsen symptoms of peptic ulcers, so patients with a history of gastrointestinal diseases should be cautious. Dizziness or fatigue may occur while driving or operating machinery, so caution is necessary. Pregnant or breastfeeding women are advised not to use this medication unless absolutely necessary and only after consultation with a specialist. The safety of this medication in children has not been established, hence it should not be used in children. This medication may interact with other drugs, so especially when used concurrently with heart-related medications, antibiotics, antidepressants, or non-steroidal anti-inflammatory drugs, inform your healthcare provider. In case of overdose, dangerous symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur, and immediate emergency treatment is required, with atropine potentially used as an antidote. This medication should be stored out of reach of children and should not be transferred to other containers.

Serious side effects

Syncope, bradycardia, heart block, prolonged QT interval, myocardial infarction, heart failure, peptic ulcer, perforated duodenal perforation, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, cerebral seizures (epilepsy, convulsions), cerebral hemorrhage, cerebrovascular disorders, neuroleptic malignant syndrome, rhabdomyolysis, respiratory distress, acute pancreatitis, acute renal failure, unexplained sudden death, cardiac arrest, urticaria, severe swelling (edema), chest...

Mild side effects

• Headache
• dizziness
• insomnia
• diarrhea
• nausea
• vomiting
• loss of appetite
• fatigue
• muscle pain
• rash

This medication should be stored in an airtight container to prevent exposure to air or moisture. The storage temperature should be maintained at room temperature between 1°C and 30°C.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle