Diaren Capsule (Diacerein)

Adult dose

Adults: Administer 50∼100mg of diacerein orally per day in 1∼2 divided doses after meals. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg 2 times daily.

This medication should not be used in patients with certain conditions. For example, individuals with inflammatory bowel disease or intestinal obstruction syndrome should not take this medication. People experiencing unexplained abdominal pain should also avoid this medication, as should those allergic to this drug or its ingredients. It should not be administered to individuals with liver disease or a history of liver disease, as well as children under 15 years of age. Additionally, this medication contains lactose, and individuals with genetic disorders affecting lactose digestion should avoid it. Use this medication with caution in individuals with a history of small intestine or colon disease, pregnant or breastfeeding women, and the elderly over 65 years of age. In particular, dosage reduction may be necessary for older adults. People who have had allergic reactions or hypersensitivity to any coloring agents in this medication should also exercise caution. Gastrointestinal side effects may occur during use, such as diarrhea, abdominal pain, and loose stools. Long-term use may lead to serious issues such as gastrointestinal bleeding, ulcers, or perforation. Severe diarrhea can lead to dehydration or electrolyte imbalance; if such symptoms occur, discontinue use immediately and consult a doctor. Skin symptoms such as itching, rash, or dermatitis may appear, and there is a potential risk of impaired liver function, making liver health monitoring necessary. When using this medication long-term, it must be done strictly under medical supervision; if diarrhea occurs, discontinue use immediately and seek medical attention. Avoid alcohol consumption as it can burden the liver. If impaired liver function symptoms are suspected, consult a doctor immediately. This medication may hinder absorption when taken with antacids containing calcium, magnesium, or aluminum, so it should be taken at least 2 hours apart from these drugs. Additionally, co-administration with diuretics may increase diuretic effects, posing a risk of dehydration or hypokalemia. Increased risk of arrhythmias may occur when taken with cardiac glycosides, so it is essential to discuss with a doctor. Pregnant women should avoid taking this medication as it may affect fetal bone formation. Breastfeeding women should also refrain from use as the drug may be transmitted through breast milk. In case of overdose, severe diarrhea may occur; if this happens, seek immediate medical attention for electrolyte replenishment and appropriate treatment.

Diarrhea, loose stools, abdominal pain, gastrointestinal disorders (bleeding, ulcers, and perforation), pigmentation of the rectal mucosa, dehydration, fluid and electrolyte imbalance, itching, rash, eczema, elevated liver enzymes in serum, hypokalemia, symptoms of liver damage, severe diarrhea

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is best kept at temperatures between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance

A hard capsule with a yellow upper part and a light yellow lower part containing a brownish powder.

Package unit

30 capsules/bottle, 500 capsules/bottle