Olmesartan Medoxomil and S-Amlodipine Tablets 2.5/20 mg

Adult dose

This medication is administered once daily, with one tablet taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). The initial dosage is 2.5/20 mg, which can be increased to 2.5/40 mg or 5/40 mg depending on blood pressure control. Careful dosage adjustments are required for patients with renal impairment, reduced effective circulating blood volume, hepatic impairment, or elderly patients.

Child dose

Safety and efficacy have not been established for pediatric patients under 18 years of age.

This medication can cause severe harm to the fetus and newborn if taken during pregnancy, especially in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. Individuals with allergies to this drug's active ingredients or similar components, pregnant or nursing women, patients with severe liver or kidney diseases, and patients with certain heart diseases should not take this medication. Patients with hypotension due to insufficient fluid or salt may experience initial hypotensive symptoms during the start of this medication, so they should begin taking it under careful observation. This medication may cause rare acute hypotension due to vasodilation, so patients with vascular stenosis should be particularly cautious. Patients with heart failure or obstructive coronary artery disease may see an exacerbation of cardiac symptoms when taking this drug, hence it should be used cautiously. Patients with impaired kidney function may see further deterioration in kidney function while on this medication, requiring regular kidney function tests. Patients with reduced liver function also need to be cautious while taking this medication, and dosage adjustments may be necessary. This medication can cause various adverse reactions, commonly including dizziness, headache, hypotension, edema, indigestion, and others. There may be interactions with other medications, so it is essential to inform the doctor or pharmacist about any other medications being taken. Taking this medication during pregnancy can lead to serious issues for the fetus, so alternative medications should be considered if planning to conceive or already pregnant. If breastfeeding, there is a possibility that this medication may be transmitted through breast milk, so it is advisable to stop breastfeeding or the medication. Safety and effectiveness for patients under 18 years have not been established, so it is not recommended. Elderly patients may have increased drug concentrations in their body due to reduced kidney and liver function, so it is necessary to start at a low dose and adjust it carefully. Overdose can result in hypotension and cardiac dysfunction, requiring immediate medical attention.

Serious side effects

• Urticaria
• angioedema
• urticaria
• alopecia
• angioedema
• severe swelling (edema)
• palpitations
• dyspnea
• difficulty breathing
• seizures

Mild side effects

• Hyperkalemia
• decreased libido
• dizziness
• headache
• orthostatic hypotension
• drowsiness
• paresthesia
• sensory impairment
• fainting
• vertigo

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. Additionally, it should be kept away from excessively hot or cold areas, ideally at room temperature between 1 to 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets, 300 tablets