Esomeprazole 40 mg Tablets (Esomeprazole Magnesium Trihydrate)

Adult dosage

This drug should be swallowed with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 20 mg once daily 2) Helicobacter pylori eradication combined therapy

Children's dosage

Adolescents aged 12 and older 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: once daily,

This drug should not be administered to specific patients. Patients with an allergy or hypersensitivity to this drug or any of its components, or to benzimidazole derivatives should not use it. Additionally, it should be avoided in patients with allergy to amoxicillin or clarithromycin when used in combination therapy for eradication of Helicobacter pylori. Patients on cardiac medications or with a history of myocardial infarction, as well as breastfeeding women, should preferably not use this medication. This drug may cause various adverse reactions. Symptoms such as decreased blood cell count, allergic reactions, hypomagnesemia, headache, dizziness, abdominal pain, diarrhea, abnormal liver function, skin rash have been reported. Notably, prolonged use may lead to hypomagnesemia, necessitating regular blood tests. This drug inhibits gastric acid secretion, which lowers stomach acidity, but this may slightly increase the risk of bacterial infections in the gastrointestinal tract. Long-term use may also increase the risk of fractures, so caution is required for patients with osteoporosis. This drug may interact with other medications, so especially when used in combination with antibiotics, antiviral agents, anticoagulants, anticonvulsants, consultation with a doctor or pharmacist is necessary. Changes in drug concentration may require dosage adjustment or monitoring if necessary. Due to limited data on the safety of this drug during pregnancy, pregnant women should use it cautiously, and nursing mothers are advised not to take it. In case of overdose, there is no specific antidote, so treatment should be symptomatic and based on general management. This drug should be stored in a safe place out of reach of children, and transferring it to another container is not advisable as it may affect the quality.

Serious side effects

Urticaria, angioedema, anaphylactic reaction, shock, angioedema, yellowing of the skin or eyes (jaundice), hepatitis, liver failure, encephalopathy in patients with pre-existing liver disease, skin-mucous membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), Clostridium difficile-associated diarrhea, respiratory distress, asthma attack

Mild side effects

• Headache
• dizziness
• paresthesia
• drowsiness
• taste disturbance
• blurred vision
• bronchospasm
• abdominal pain
• constipation
• diarrhea

This drug must be stored in a sealed container to prevent exposure to air or moisture. It should be stored at room temperature between 1 degree and 30 degrees Celsius for safe use.

Appearance

Pink, round, film-coated tablet

Package unit

28 tablets (14 tablets/PTP X 2)