Nexpazole Tablet 20 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1) Treatment of gastroesophageal reflux disease (GERD) - Erosive esophagitis: 40 mg once daily for 4 weeks. - If not cured or symptoms persist, an additional 4 weeks of medication may be taken. - Maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily. - Treatment of symptoms without esophagitis: once daily dosing at 20 mg.

Children's dosage

Adolescents 12 years and older - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. - If not cured or symptoms persist, an additional 4 weeks of medication may be taken. - Treatment of symptoms without esophagitis

This medication should not be used in patients with hypersensitivity to specific ingredients or benzimidazole derivatives, or those who have experienced such reactions in the past. Patients with allergies to penicillin-type antibiotics or macrolide antibiotics should also exercise caution, especially when used in combination for the eradication of Helicobacter pylori. Furthermore, patients who are taking some cardiac-related medications or antivirals, as well as those who are nursing or have a history of myocardial infarction, should not use this medication. This medication contains a dye called Yellow No. 5, so patients with allergies or sensitivity to this ingredient should be careful. During use, various side effects such as rare blood-related abnormal symptoms or allergic reactions, electrolyte imbalance, mental changes, headaches, gastrointestinal issues may occur, so immediate consultation with healthcare professionals is necessary if such symptoms arise. It is important to undergo regular examinations to check for abnormalities during long-term use. This medication suppresses gastric acid secretion and may promote bacterial growth in the stomach, which can increase the risk of certain bacterial infections. Additionally, long-term use may increase the risk of fractures, so patients at risk for osteoporosis should exercise caution. Magnesium levels may decrease, so patients taking this medication long-term should periodically check their blood magnesium concentration. Due to potential drug interactions, there may be changes in drug concentration or the risk of side effects when used in combination with other medications, so it is essential to inform healthcare professionals about all medications being taken. During pregnancy, safety has not been sufficiently established; it should be used cautiously only when necessary, and it is advisable not to take this medication during breastfeeding. In case of overdose, there is no specific antidote, and appropriate treatment should be conducted based on symptoms, and it should be kept out of reach of children.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, shock, fever (related to hypersensitivity), jaundice, hepatitis, liver failure, encephalopathy, severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, DRESS syndrome), severe edema, shortness of breath, bronchospasm, asthma exacerbation, serious neurological symptoms (seizures), systemic lupus erythematosus, cutaneous lupus erythematosus

Mild side effects

• Leukopenia
• thrombocytopenia
• agranulocytosis
• pancytopenia
• fever
• peripheral edema
• hyponatremia
• hypomagnesemia
• insomnia
• anxiety

This medication must be stored in a tightly sealed container to protect it from exposure to air or moisture. It is also safest to store it at a cool room temperature between 1 degree and 30 degrees.

Appearance

Pale pink oval film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu * 2)