Cenex Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medication should be adjusted for each patient, and it may be taken with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily or 100 mg twice daily. 2. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks at 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose as needed is 200 mg twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

Patients who regularly consume more than three glasses of alcohol daily should consult a physician or pharmacist before taking this medication. Taking this medication while consuming large amounts of alcohol may increase the risk of gastrointestinal bleeding. This medication may increase the risk of cardiovascular thrombotic events, such as serious heart and cerebrovascular issues like myocardial infarction or stroke. The risk may increase with higher doses and longer duration of use, so it is important to use the minimum effective dose for the shortest duration possible. There are also gastrointestinal risks, including perforation, ulcers, or bleeding in the stomach or intestines. Special caution is advised for the elderly or those with a history of gastrointestinal disorders, and if symptoms such as epigastric pain, indigestion, blood in stool, or vomiting of blood occur, immediate consultation with a healthcare professional is necessary. This medication is contraindicated in individuals with a history of allergic reactions or allergy to sulfonamides, and those with asthma or certain heart and kidney diseases, as well as women who are pregnant or breastfeeding. Patients with impaired liver or kidney function, hypertension, heart failure, diabetes, or the elderly require special caution when using this medication, and liver and kidney functions should be regularly monitored through tests. This medication may interact with other drugs, so it is essential to consult with a physician when taken with blood pressure medications, diuretics, anticoagulants, antidepressants, lithium, or methotrexate, and dosage adjustments may be needed. Women who are pregnant or planning to become pregnant should avoid taking this medication, and if pregnancy occurs during treatment, it should be stopped immediately and a physician consulted. This medication can also be excreted in breast milk, so caution is necessary for nursing mothers. Dizziness or drowsiness may occur during treatment, so it is advisable to avoid driving or operating machinery. Long-term use of this medication requires regular blood tests and monitoring of liver and kidney functions, and if abnormal symptoms appear, healthcare professionals should be notified immediately. Overdosage may result in symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding, necessitating immediate medical attention. Keep this medication out of reach of children and do not transfer it to other containers.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional states, dizziness, muscle spasticity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injuries, taste disorders, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, incontinence, urinary tract infections, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of smell, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash accompanied by eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, menstrual disorders, female infertility, chest pain, dyspepsia, diarrhea, headache, dizziness, constipation, gastric ulcer, urticaria, anemia, thirst, ulcerative stomatitis, gastritis, allergy, back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive rheumatoid factor, herpes zoster, pneumonia, dyspnea, elevated ALT, hearing loss, weakness, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, loss of appetite, increased appetite, depression, neurosensitivity, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, confusion, hallucination, bronchospasm, exacerbation of bronchospasm, laryngitis, pneumonia, nosebleed, voice disorders, vesicular dermatitis, dermatitis, nail disorders, photosensitivity reaction, pruritus, erythematous rash, maculopapular rash, skin diseases, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, vasculitis, thrombophlebitis, deep vein thrombosis, cerebral hemorrhage, vasculitis, thrombophlebitis, deep vein thrombosis, cerebral hemorrhage

Store this medication in a tightly sealed container to prevent air or moisture ingress, ideally in a cool place between 15 to 30 degrees Celsius. Proper storage can help maintain the effectiveness of the medication for a longer period.

Appearance

A white capsule filled with white to light yellow powder, with a blue stripe on the upper and lower parts.

Package unit

30 capsules/bottle, 100 capsules/bottle