Alniz Tablet

Adult dose

Usually taken 2 tablets 2 times a day in the morning and before bedtime, regardless of meals. For gastric ulcer and duodenal ulcer: administer 2 tablets 2 times a day or 4 tablets once before bedtime. Especially for patients with duodenal ulcers, taking 4 tablets 2 times a day in the morning and before bedtime can achieve a higher treatment rate. In cases of ulcers caused by non-steroidal anti-inflammatory drugs, the same dosage is used for the combination therapy to prevent gastric and duodenal ulcers due to long-term use of non-steroidal anti-inflammatory drugs. Generally, diseases caused by non-steroidal anti-inflammatory drugs heal within 8 weeks, but in some cases, the healing period may be extended depending on individual patients. For patients with recurrent ulcers, who have shown excellent results with short-term therapy, 2 tablets once a day before bedtime is administered as maintenance therapy. For gastroesophageal reflux disease: administer 2 tablets 2 times a day or 4 tablets once before bedtime for 8 weeks. For patients with severe gastroesophageal reflux disease, the dosage can be increased to 4 tablets 4 times a day. For Zollinger-Ellison syndrome: start treatment with an initial dose of 2 tablets 3 times a day and adjust the dose as needed; in severe cases, a doctor may prescribe up to 6g of ranitidine per day. For upper gastrointestinal bleeding from acute gastric lesions or gastric stress ulcers: once oral intake is possible, switch from injection to oral administration of 2 tablets 2 times a day. Administer 2 tablets 2 hours before anesthesia induction. In this case, it is also recommended to take 2 tablets the night before the surgery.

Child dose

For children aged 8-18 years, take 2 tablets (2 mg/kg of ranitidine) up to 2 times a day.

This medicine should not be used in patients undergoing dialysis treatment. Patients allergic to ranitidine hydrochloride should not take this medicine. For patients with impaired renal function, the drug may remain in the body for a long time, so the dosage should be reduced or the dosing interval should be increased for careful use. Caution is also required for patients with liver dysfunction when using this medicine. Patients with a history of drug allergies and the elderly should be careful when taking this medicine. Rarely, severe allergic reactions such as shock may occur while taking this medicine; if symptoms appear, immediately discontinue the medication and seek medical attention. If allergic symptoms such as rash, hives, swelling of the face or neck, fever, shortness of breath, or low blood pressure occur, stop taking the medicine and consult a doctor. A blood test may show a decrease in white blood cells or platelets, and liver function test values may temporarily rise. Irregular heartbeat or symptoms of fast or slow heart rate have been reported rarely. Digestive symptoms may include nausea, vomiting, constipation, diarrhea, abdominal bloating, and abdominal pain, and stool color may change, but this does not require special treatment. Nervous system symptoms such as dizziness, drowsiness, confusion, seizures, anxiety, depression, hallucinations, insomnia, and headaches may appear rarely. Gynecomastia or sexual dysfunction has been reported, but the direct relation to this medicine is not clear. Joint pain, rash including mild polymorphic erythema, hair loss, and itching may occur, but these symptoms are mostly temporary. It is advisable not to use this medicine for a long time, and patients with a history of kidney disease should consult a doctor or pharmacist before taking it. Monitor the treatment's progress and use the minimum effective dose; if there is no effect, it should be changed to another medication. Women who are pregnant or may become pregnant should only take this medicine when the benefits of treatment outweigh the risks, as its safety is not guaranteed. This medicine may be transmitted through breast milk, so breastfeeding should be avoided during treatment. Safety in children has not been sufficiently established, so it should be used cautiously in children. Some urine tests may yield false-positive results, so it is advisable to use specific test methods for accurate testing. In case of overdose, emergency measures such as vomiting or gastric lavage may be necessary, and if needed, the drug can be removed through hemodialysis. This medicine can mask symptoms of gastric cancer, so it should only be used after confirming whether it is malignant. Long-term use may affect the eyes, so it is advisable to have regular ophthalmic examinations while using it.

Serious side effects

Shock (severe allergic reaction), angioedema (severe allergic reaction), agranulocytosis, pancytopenia, bone marrow failure, aplastic anemia, jaundice or non-jaundice hepatitis (liver dysfunction), arrhythmia, reversible jaundice, confusional state, visual disturbances, paralysis

Mild side effects

Skin rash, hives, fever, bronchospasm, hypotension, reversible leukopenia, decreased platelets, increased serum enzyme levels, nausea, vomiting, constipation, diarrhea, abdominal bloating, abdominal pain, loss of appetite, stool discoloration, dizziness, drowsiness, confusion, seizures, agitation, depression, hallucinations, insomnia, headache, heaviness, malaise, gynecomastia, impotence, sexual dysfunction, joint pain, mild polymorphic erythema including rashes, hair loss, skin itching,

This medicine should be stored in a tightly closed container to prevent air or moisture from entering. It is important to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Green round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle