Espas Tablet 4 mg (Silodosin)

Adult dose

Adults: Administer orally either 1 tablet of 4mg twice daily after breakfast and dinner, or 2 tablets of 4mg (8mg) once daily with a meal. However, increased plasma concentrations of silodosin have been reported in patients with renal impairment, and plasma concentrations may also increase in patients with hepatic impairment. Therefore, monitor the patient's condition and adjust the dose as appropriate according to symptoms, including initiating treatment at a low dose (2mg per dose, twice daily).

This medication should not be used by patients with known allergies to any of its components, severe renal impairment, or severe hepatic dysfunction. Additionally, patients taking strong CYP3A4 enzyme inhibitors should avoid concomitant use. Caution is advised when administering to patients with orthostatic hypotension symptoms or those with slight impairment of liver or kidney function. Patients taking antihypertensives, other alpha-blockers, and PDE5 inhibitors should be cautious as blood pressure may drop excessively when taken together. During the use of this medication, side effects such as ejaculation disorders, dizziness, headaches, dry mouth, diarrhea, nasal congestion may occur; if any abnormalities present, consult a medical professional immediately. In particular, there may be instances of sudden blood pressure drop causing fainting, hence care is required with changes in position, and caution is advised when driving or performing hazardous tasks. Overdose may lead to hypotension, thus prescribed doses should be strictly adhered to, and blood pressure should be carefully monitored when taken with other antihypertensive medications. While this medication helps alleviate symptoms of benign prostatic hyperplasia, as symptoms may resemble those of prostate cancer, evaluation for the presence of prostate cancer should be conducted before administration. Patients planning cataract surgery must inform their healthcare provider about this medication, and it is not to be used in patients with severe liver dysfunction. This medication should be kept out of the reach of children, and transferring to another container should be avoided as it may affect the medication's quality. In elderly patients, starting with a lower dose is recommended, considering liver and kidney function, and careful observation should be maintained during dosage.

• Sexual dysfunction
• dry mouth
• diarrhea
• loose stools
• orthostatic dizziness
• nasal congestion
• lightheadedness
• dizziness
• headache
• elevated TG

This medication should be stored in a tightly sealed container that protects it from light and kept at room temperature between 1°C and 30°C. Storing it in this way helps maintain its efficacy over time.

Appearance

White round film-coated tablet

Package unit

60 tablets (10 tablets/PTP x 6)