Donepezil Tablets 5 mg (Donepezil Hydrochloride Monohydrate)

Adult dose

As Donepezil Hydrochloride, administer 5 mg once daily before bed. For 4-6 weeks, administer the 5 mg dose and evaluate clinical response before increasing to 10 mg. When increasing to 10 mg daily, be cautious of gastrointestinal adverse effects during administration. Underweight female patients over 85 years should not exceed 5 mg daily and require careful monitoring.

Child dose

There is no experience using this medication in children.

This medicine should not be used by individuals with allergies to specific components. Pregnant women, women who may become pregnant, and nursing mothers should not take this medication. Patients with genetic lactose intolerance issues are also not suitable for this medication. Patients with heart disease or cardiac conduction disorders should be cautious as this medication can cause bradycardia or arrhythmias. Patients with a history of peptic ulcers or those taking non-steroidal anti-inflammatory drugs should use this medication carefully due to the risk of gastrointestinal bleeding or worsening ulcers. Patients with asthma or chronic obstructive pulmonary disease should be cautious as bronchoconstriction or increased mucus secretion may exacerbate symptoms. Patients with extrapyramidal disorders such as Parkinson's disease should use this medication carefully as there is a risk of symptom exacerbation. This medication contains Yellow No. 5, so caution is needed for those allergic to this ingredient. During treatment, serious side effects such as cardiac irregularities, gastrointestinal bleeding, liver dysfunction, seizures, muscle pain, and respiratory difficulties may occur; consult healthcare providers immediately if any unusual symptoms arise. In the initial treatment phase or during dosage adjustments, symptoms such as dizziness, drowsiness, insomnia, nausea, vomiting, or diarrhea may occur, so caution is advised. It is recommended to be careful with activities requiring attention, such as driving or operating machinery, in the early stages of taking this medication. This medication can interact with various drugs, so if other medications are being taken, it is essential to inform healthcare providers. Particular caution is necessary when used together with heart medications, antibiotics, antidepressants, and antipsychotics. Pregnant or nursing women should avoid using this medication, and if necessary, should consult with a specialist. Safety in children has not been confirmed; thus, it is not to be used in pediatric patients. Overdose may cause severe nausea, vomiting, bradycardia, hypotension, or respiratory depression, requiring immediate medical attention. Store this medication out of reach of children and do not transfer to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in mouth/eyes mucosa, shortness of breath or difficulty breathing, asthma attack, breathing abnormalities accompanied by cough+fever, yellowing of skin or eyes (jaundice), extreme lethargy throughout the body, sudden and severe headache, lightning-like headache, seizures, confusion of consciousness, vision abnormalities, paralysis, urination abnormalities

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• fever
• insomnia
• dizziness
• drowsiness

This medication should be stored in a sealed container to prevent air or humidity from entering. Additionally, it is best stored at room temperature between 1 degree and 30 degrees.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle