Ocuronil Tablets (Nafronil Oxalate)

Adult dose

Adults: Administer nafronyl oxalate 100 mg orally per dose, 3 times daily.

This medication should not be used in patients with acute myocardial infarction or in the early stages of hemorrhagic injuries. Patients with orthostatic hypotension or those who have had allergic reactions to this medication should not take it. Patients with a history of hyperoxaluria or recurrent calcium kidney stones, or those with acute myocardial infarction or congestive heart failure should also avoid this medication. Patients with severe cardiac conduction abnormalities, angina, or severe hypotension should refrain from use. Patients with liver dysfunction or those at risk of seizures, as well as pregnant women or women who may become pregnant, and nursing mothers should not take this medication. Patients with impaired kidney function and those with coronary artery atherosclerosis should exercise caution when using this medication. This medication may cause neurological symptoms such as seizures, sensory abnormalities, anxiety, drowsiness, insomnia, headaches, and dizziness. Gastrointestinal effects may include loss of appetite, esophagitis, vomiting, nausea, abdominal pain, and diarrhea. Allergic reactions such as hives or angioedema, and rashes may occur. There may be liver-related issues such as hepatitis, jaundice, hepatic necrosis, increased liver enzymes, and rarely, liver failure. Kidney issues such as urinary disorders or calcium oxalate kidney stones can occur, so caution is necessary. Cardiovascular issues like hypotension, orthostatic hypotension, arrhythmia, angina, syncope, and peripheral edema have also been reported. Blood sugar levels may rise, so those needing blood sugar management should be cautious. This medication is not used for the treatment of hypertension and should not be used for hypertension treatment purposes. When taking this medication, it is important to stay well hydrated to reduce the risk of developing calcium oxalate kidney stones. Especially, taking the medication without any drinks before bed may lead to esophagitis, so it must be taken with water. Taking it in conjunction with antihypertensive drugs may enhance the hypotensive effects, so caution is advised. Using it alongside arrhythmia medications may enhance their effects, so consultation with a physician is necessary. It is safest for pregnant or nursing women not to take this medication. In case of overdose, cardiac suppression and seizures may occur, necessitating immediate medical treatment. If necessary, gastric lavage and activated charcoal may be administered, and monitoring of cardiac and respiratory status should be conducted. In severe cases, the use of a pacemaker or isoproterenol administration may be required. If seizures occur, they are treated with medications like diazepam.

• Cerebral convulsions
• sensory abnormalities
• anxiety
• drowsiness
• insomnia
• fatigue
• headache
• dizziness
• anorexia
• esophagitis

This medication is sensitive to light and should be stored in a container that does not allow light to enter. Additionally, to maintain the effectiveness of the medication, it is important to store it at room temperature, that is between 1 to 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle