Losiridine Sustained-Release Tablet 4 mg (Tolterodine L-Tartrate)

Adult dose

Adults: Administer 4 mg of tolterodine L-tartrate orally once daily. Patients with renal impairment, hepatic impairment, or receiving ketoconazole or another potent CYP3A4 inhibitor: Administer 2 mg of this medicine once daily. If adverse reactions occur, the dose may be reduced from 4 mg to 2 mg once daily. This medicine may be taken with or without food. Swallow the dosage form whole; do not crush or split it.

This medication contains lactose, so individuals with genetic disorders that affect lactose metabolism should not take it. Patients with certain conditions such as urinary obstruction, gastrointestinal motility disorders, uncontrolled glaucoma, severe myasthenia gravis, severe ulcerative colitis, and toxic megacolon should also avoid this medication. Patients at risk of urinary obstruction or with controlled glaucoma, gastrointestinal obstruction, or impaired liver or kidney function should use this medication cautiously, especially if they are taking certain antibiotics, antifungals, or immunosuppressants. This medication may cause side effects such as dry mouth, dyspepsia, decreased tear production, and rarely allergic reactions, headaches, dizziness, constipation, urinary difficulties, fatigue, and various adverse reactions. There is a risk of cardiac problems associated with QT interval prolongation, so caution is advised for those with related conditions or taking medications that prolong the QT interval. This medication can affect concentration and reaction speed, so caution is needed when driving or operating machinery. Combining with other antimuscarinic medications may enhance effects, and concurrent use with drugs that inhibit certain metabolic enzymes may increase blood concentrations, so be mindful of drug interactions. Pregnant or breastfeeding women should not use this medication, and contraception is advised during pregnancy due to potential harm to the fetus. Safety and efficacy in pediatric patients have not been sufficiently established. In case of overdose, symptoms such as visual disturbances, urinary difficulties, and central nervous system abnormalities may occur, and immediate medical attention should be sought. This medication should be stored out of reach of children and not transferred to other containers to maintain quality.

• dry mouth
• indigestion
• decreased tear production
• bronchitis
• allergic reaction
• confusion
• drowsiness
• dizziness
• headache
• hypersensitivity

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. Additionally, it is best to store the medication at room temperature below 25 degrees Celsius. This helps maintain the medication's efficacy over time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle