Sitagliptin and Metformin Tablets 50/850 mg

Adult dosage

This medication is generally taken twice daily with food, and the dosage may be gradually increased to reduce gastrointestinal adverse effects related to metformin. 1. Patients not currently receiving treatment with metformin: - Initial dosage is 50/500 mg twice daily, taking 1 tablet at a time. - For dosage escalation, 50/1000 mg twice daily, taking 1 tablet at a time. 2. Patients currently receiving metformin treatment: -

This medication is used for diabetes treatment and contains two active ingredients. The first ingredient helps in controlling blood sugar, while the second ingredient promotes insulin secretion to reduce blood sugar levels. Before taking this medication, it is essential to verify if there have been any allergic reactions in the past. If symptoms such as skin rash, hives, or difficulty breathing occur, discontinue use immediately and consult a doctor. Severe pancreatic disease known as acute pancreatitis may occur, so it is important to inform healthcare personnel immediately if symptoms include abdominal pain, vomiting, or nausea during treatment. Patients with severely impaired kidney function or specific health conditions such as severe infection, dehydration, or heart failure should not take this medication. Before tests involving radiologic contrast agents, the use of this medication should be temporarily suspended, and it should be restarted only after confirming normal kidney function post-examination. It is advisable for pregnant or potentially pregnant women, as well as nursing mothers, to refrain from using this medication. This medication may cause hypoglycemia; hence, blood sugar levels should be closely monitored in cases of irregular meals, excessive exercise, or concomitant use with other hypoglycemic agents. During treatment, gastrointestinal symptoms such as diarrhea, nausea, vomiting, and headache can occur, and severe joint pain or skin blistering may also arise as adverse reactions. Alcohol consumption may increase the risk of side effects from this medication, so it is recommended to avoid drinking while on treatment. Patients taking this medication should have regular blood tests and kidney function evaluations, including periodic checks of vitamin B12 levels. In cases of overdose, individuals should visit a medical institution immediately for appropriate treatment, as some ingredients may be removed through hemodialysis. Patients on this medication should be cautious of hypoglycemic symptoms while driving or operating machinery and may need to consult their doctor for dosage adjustments.

Serious side effects

Hives, angioedema, anaphylaxis, exfoliative skin diseases (including Stevens-Johnson syndrome), acute pancreatitis, acute renal failure, difficulty breathing, severe swelling (edema), severe and disabling joint pain, vesicular pemphigoid, thrombocytopenia, elevated liver enzyme levels, acute renal failure, difficulty breathing, unstable angina, acute renal failure, lactic acidosis, cold sweats, pallor

Mild side effects

• Headache
• upper respiratory tract infection
• nasopharyngitis
• diarrhea
• nausea
• vomiting
• abdominal pain
• muscle pain
• limb pain
• back pain

Store this medication in a tightly sealed container to prevent exposure to air or moisture, and keep it at a temperature between 1 and 30 degrees Celsius. This will help maintain the medication's efficacy and ensure safe use.

Appearance

Pink oval film-coated tablet

Package unit

28 tablets (14 tablets/PTP × 2)